Largaespada D - Search Results

1

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress.

Yun YS, Kim KH, Tschida B, Sachs Z, Noble-Orcutt KE, Moriarity BS, Ai T, Ding R, Williams J, Chen L, Largaespada D, Kim DH. Yun YS, et al. Among authors: largaespada d. Mol Cell. 2016 Feb 18;61(4):625-639. doi: 10.1016/j.molcel.2016.01.013. Epub 2016 Feb 11. Mol Cell. 2016. PMID: 26876939 Free PMC article.

2

Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system.

Keng VW, Tschida BR, Bell JB, Largaespada DA. Keng VW, et al. Hepatology. 2011 Mar;53(3):781-90. doi: 10.1002/hep.24091. Epub 2011 Jan 3. Hepatology. 2011. PMID: 21374658 Free PMC article.

3

Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells.

Wilber A, Ulloa Montoya F, Hammer L, Moriarity BS, Geurts AM, Largaespada DA, Verfaillie CM, McIvor RS, Lakshmipathy U. Wilber A, et al. Stem Cells Int. 2011;2011:717069. doi: 10.4061/2011/717069. Epub 2011 Oct 2. Stem Cells Int. 2011. PMID: 21977042 Free PMC article.

4

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.

Keng VW, Rahrmann EP, Watson AL, Tschida BR, Moertel CL, Jessen WJ, Rizvi TA, Collins MH, Ratner N, Largaespada DA. Keng VW, et al. Cancer Res. 2012 Jul 1;72(13):3405-13. doi: 10.1158/0008-5472.CAN-11-4092. Epub 2012 Jun 14. Cancer Res. 2012. PMID: 22700876 Free PMC article.

5

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

Keng VW, Sia D, Sarver AL, Tschida BR, Fan D, Alsinet C, Solé M, Lee WL, Kuka TP, Moriarity BS, Villanueva A, Dupuy AJ, Riordan JD, Bell JB, Silverstein KA, Llovet JM, Largaespada DA. Keng VW, et al. Among authors: largaespada da. Hepatology. 2013 Jan;57(1):120-30. doi: 10.1002/hep.26004. Epub 2012 Oct 19. Hepatology. 2013. PMID: 22899566 Free PMC article.

6

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

Keng VW, Watson AL, Rahrmann EP, Li H, Tschida BR, Moriarity BS, Choi K, Rizvi TA, Collins MH, Wallace MR, Ratner N, Largaespada DA. Keng VW, et al. Sarcoma. 2012;2012:620834. doi: 10.1155/2012/620834. Epub 2012 Dec 18. Sarcoma. 2012. PMID: 23319880 Free PMC article.

7

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

Moriarity BS, Rahrmann EP, Keng VW, Manlove LS, Beckmann DA, Wolf NK, Khurshid T, Bell JB, Largaespada DA. Moriarity BS, et al. Nucleic Acids Res. 2013 Apr;41(8):e92. doi: 10.1093/nar/gkt115. Epub 2013 Feb 26. Nucleic Acids Res. 2013. PMID: 23444141 Free PMC article.

8

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance.

Watson AL, Rahrmann EP, Moriarity BS, Choi K, Conboy CB, Greeley AD, Halfond AL, Anderson LK, Wahl BR, Keng VW, Rizzardi AE, Forster CL, Collins MH, Sarver AL, Wallace MR, Schmechel SC, Ratner N, Largaespada DA. Watson AL, et al. Among authors: largaespada da. Cancer Discov. 2013 Jun;3(6):674-89. doi: 10.1158/2159-8290.CD-13-0081. Epub 2013 Mar 27. Cancer Discov. 2013. PMID: 23535903 Free PMC article.

9

Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis.

Riordan JD, Keng VW, Tschida BR, Scheetz TE, Bell JB, Podetz-Pedersen KM, Moser CD, Copeland NG, Jenkins NA, Roberts LR, Largaespada DA, Dupuy AJ. Riordan JD, et al. Among authors: largaespada da. PLoS Genet. 2013 Apr;9(4):e1003441. doi: 10.1371/journal.pgen.1003441. Epub 2013 Apr 4. PLoS Genet. 2013. PMID: 23593033 Free PMC article.

10

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.

Rahrmann EP, Watson AL, Keng VW, Choi K, Moriarity BS, Beckmann DA, Wolf NK, Sarver A, Collins MH, Moertel CL, Wallace MR, Gel B, Serra E, Ratner N, Largaespada DA. Rahrmann EP, et al. Nat Genet. 2013 Jul;45(7):756-66. doi: 10.1038/ng.2641. Epub 2013 May 19. Nat Genet. 2013. PMID: 23685747 Free PMC article.

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