Plückthun A - Search Results

1

Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.

Hansen S, Tremmel D, Madhurantakam C, Reichen C, Mittl PR, Plückthun A. Hansen S, et al. Among authors: pluckthun a. J Am Chem Soc. 2016 Mar 16;138(10):3526-32. doi: 10.1021/jacs.6b00099. Epub 2016 Mar 2. J Am Chem Soc. 2016. PMID: 26878586

2

Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex.

Tissot AC, Ciatto C, Mittl PR, Grütter MG, Plückthun A. Tissot AC, et al. Among authors: pluckthun a. J Mol Biol. 2000 Sep 29;302(4):873-85. doi: 10.1006/jmbi.2000.4501. J Mol Biol. 2000. PMID: 10993729

3

In vitro selection for catalytic activity with ribosome display.

Amstutz P, Pelletier JN, Guggisberg A, Jermutus L, Cesaro-Tadic S, Zahnd C, Plückthun A. Amstutz P, et al. Among authors: pluckthun a. J Am Chem Soc. 2002 Aug 14;124(32):9396-403. doi: 10.1021/ja025870q. J Am Chem Soc. 2002. PMID: 12167034

4

A novel strategy to design binding molecules harnessing the modular nature of repeat proteins.

Forrer P, Stumpp MT, Binz HK, Plückthun A. Forrer P, et al. Among authors: pluckthun a. FEBS Lett. 2003 Mar 27;539(1-3):2-6. doi: 10.1016/s0014-5793(03)00177-7. FEBS Lett. 2003. PMID: 12650916 Free article.

5

Designing repeat proteins: modular leucine-rich repeat protein libraries based on the mammalian ribonuclease inhibitor family.

Stumpp MT, Forrer P, Binz HK, Plückthun A. Stumpp MT, et al. Among authors: pluckthun a. J Mol Biol. 2003 Sep 12;332(2):471-87. doi: 10.1016/s0022-2836(03)00897-0. J Mol Biol. 2003. PMID: 12948496

6

Consensus design of repeat proteins.

Forrer P, Binz HK, Stumpp MT, Plückthun A. Forrer P, et al. Among authors: pluckthun a. Chembiochem. 2004 Feb 6;5(2):183-9. doi: 10.1002/cbic.200300762. Chembiochem. 2004. PMID: 14760739 Review.

7

Strategies for selection from protein libraries composed of de novo designed secondary structure modules.

Matsuura T, Plückthun A. Matsuura T, et al. Among authors: pluckthun a. Orig Life Evol Biosph. 2004 Feb;34(1-2):151-7. doi: 10.1023/b:orig.0000009836.86519.eb. Orig Life Evol Biosph. 2004. PMID: 14979652 Free article.

8

High-affinity binders selected from designed ankyrin repeat protein libraries.

Binz HK, Amstutz P, Kohl A, Stumpp MT, Briand C, Forrer P, Grütter MG, Plückthun A. Binz HK, et al. Among authors: pluckthun a. Nat Biotechnol. 2004 May;22(5):575-82. doi: 10.1038/nbt962. Epub 2004 Apr 18. Nat Biotechnol. 2004. PMID: 15097997

9

Crystal structure of a consensus-designed ankyrin repeat protein: implications for stability.

Binz HK, Kohl A, Plückthun A, Grütter MG. Binz HK, et al. Among authors: pluckthun a. Proteins. 2006 Nov 1;65(2):280-4. doi: 10.1002/prot.20930. Proteins. 2006. PMID: 16493627

10

A designed ankyrin repeat protein evolved to picomolar affinity to Her2.

Zahnd C, Wyler E, Schwenk JM, Steiner D, Lawrence MC, McKern NM, Pecorari F, Ward CW, Joos TO, Plückthun A. Zahnd C, et al. Among authors: pluckthun a. J Mol Biol. 2007 Jun 15;369(4):1015-28. doi: 10.1016/j.jmb.2007.03.028. Epub 2007 Mar 20. J Mol Biol. 2007. PMID: 17466328

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