Chibale K - Search Results

1

Cyclopalladated organosilane-tethered thiosemicarbazones: novel strategies for improving antiplasmodial activity.

Adams M, Barnard L, de Kock C, Smith PJ, Wiesner L, Chibale K, Smith GS. Adams M, et al. Among authors: chibale k. Dalton Trans. 2016 Apr 7;45(13):5514-20. doi: 10.1039/c5dt04918k. Epub 2016 Feb 25. Dalton Trans. 2016. PMID: 26911403

2

Synthesis of totarol amino alcohol derivatives and their antiplasmodial activity and cytotoxicity.

Clarkson C, Musonda CC, Chibale K, Campbell WE, Smith P. Clarkson C, et al. Among authors: chibale k. Bioorg Med Chem. 2003 Oct 1;11(20):4417-22. doi: 10.1016/s0968-0896(03)00491-7. Bioorg Med Chem. 2003. PMID: 13129578

3

Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.

Musonda CC, Taylor D, Lehman J, Gut J, Rosenthal PJ, Chibale K. Musonda CC, et al. Among authors: chibale k. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3901-5. doi: 10.1016/j.bmcl.2004.05.063. Bioorg Med Chem Lett. 2004. PMID: 15225694

4

Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives.

Chiyanzu I, Clarkson C, Smith PJ, Lehman J, Gut J, Rosenthal PJ, Chibale K. Chiyanzu I, et al. Among authors: chibale k. Bioorg Med Chem. 2005 May 2;13(9):3249-61. doi: 10.1016/j.bmc.2005.02.037. Bioorg Med Chem. 2005. PMID: 15809160

5

Exploiting a basic chemosensitizing pharmacophore hypothesis. Part 1: synthesis and biological evaluation of novel arylbromide and bicyclic chemosensitizers against drug-resistant malaria parasites.

Chouteau F, Ramanitrahasimbola D, Rasoanaivo P, Chibale K. Chouteau F, et al. Among authors: chibale k. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3024-8. doi: 10.1016/j.bmcl.2005.04.033. Bioorg Med Chem Lett. 2005. PMID: 15908208

6

Reversal of chloroquine resistance in Plasmodium falciparum by 9H-xanthene derivatives.

Wu CP, van Schalkwyk DA, Taylor D, Smith PJ, Chibale K. Wu CP, et al. Among authors: chibale k. Int J Antimicrob Agents. 2005 Aug;26(2):170-5. doi: 10.1016/j.ijantimicag.2005.04.018. Int J Antimicrob Agents. 2005. PMID: 16009536

7

Arylpiperazines displaying preferential potency against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum.

Molyneaux CA, Krugliak M, Ginsburg H, Chibale K. Molyneaux CA, et al. Among authors: chibale k. Biochem Pharmacol. 2005 Dec 19;71(1-2):61-8. doi: 10.1016/j.bcp.2005.10.023. Epub 2005 Nov 18. Biochem Pharmacol. 2005. PMID: 16298348

8

Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol.

Musonda CC, Gut J, Rosenthal PJ, Yardley V, Carvalho de Souza RC, Chibale K. Musonda CC, et al. Among authors: chibale k. Bioorg Med Chem. 2006 Aug 15;14(16):5605-15. doi: 10.1016/j.bmc.2006.04.035. Epub 2006 May 11. Bioorg Med Chem. 2006. PMID: 16690319

9

Dual-acting diamine antiplasmodial and chloroquine resistance modulating agents.

Yeh S, Smith PJ, Chibale K. Yeh S, et al. Among authors: chibale k. Biochem Pharmacol. 2006 Jul 14;72(2):156-65. doi: 10.1016/j.bcp.2006.04.006. Epub 2006 Apr 25. Biochem Pharmacol. 2006. PMID: 16730664

10

Synthesis and biological evaluation of phenolic Mannich bases of benzaldehyde and (thio)semicarbazone derivatives against the cysteine protease falcipain-2 and a chloroquine resistant strain of Plasmodium falciparum.

Chipeleme A, Gut J, Rosenthal PJ, Chibale K. Chipeleme A, et al. Among authors: chibale k. Bioorg Med Chem. 2007 Jan 1;15(1):273-82. doi: 10.1016/j.bmc.2006.09.055. Epub 2006 Sep 29. Bioorg Med Chem. 2007. PMID: 17052908

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