Orr ME - Search Results

1

Reaching Out to Send a Message: Proteins Associated with Neurite Outgrowth and Neurotransmission are Altered with Age in the Long-Lived Naked Mole-Rat.

Triplett JC, Swomley AM, Kirk J, Grimes KM, Lewis KN, Orr ME, Rodriguez KA, Cai J, Klein JB, Buffenstein R, Butterfield DA. Triplett JC, et al. Among authors: orr me. Neurochem Res. 2016 Jul;41(7):1625-34. doi: 10.1007/s11064-016-1877-1. Epub 2016 Mar 2. Neurochem Res. 2016. PMID: 26935741

2

Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology.

Orr ME, Salinas A, Buffenstein R, Oddo S. Orr ME, et al. Neurobiol Aging. 2014 Jun;35(6):1233-42. doi: 10.1016/j.neurobiolaging.2013.12.006. Epub 2013 Dec 14. Neurobiol Aging. 2014. PMID: 24411482 Free PMC article.

3

Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.

Orr ME, Garbarino VR, Salinas A, Buffenstein R. Orr ME, et al. Neurobiol Aging. 2015 Mar;36(3):1496-504. doi: 10.1016/j.neurobiolaging.2014.12.004. Epub 2014 Dec 12. Neurobiol Aging. 2015. PMID: 25576082 Free PMC article.

4

Mechanisms of oxidative stress resistance in the brain: Lessons learned from hypoxia tolerant extremophilic vertebrates.

Garbarino VR, Orr ME, Rodriguez KA, Buffenstein R. Garbarino VR, et al. Among authors: orr me. Arch Biochem Biophys. 2015 Jun 15;576:8-16. doi: 10.1016/j.abb.2015.01.029. Epub 2015 Apr 1. Arch Biochem Biophys. 2015. PMID: 25841340 Free PMC article. Review.

5

Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

Triplett JC, Swomley A, Kirk J, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Buffenstein R, Butterfield DA. Triplett JC, et al. J Neurochem. 2015 Aug;134(3):538-50. doi: 10.1111/jnc.13149. Epub 2015 Jun 3. J Neurochem. 2015. PMID: 25940666 Free article.

6

Triplett JC, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, Orr M, Rodriguez K, Cai J, Klein JB, Perluigi M, Buffenstein R, Butterfield DA. Triplett JC, et al. Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2213-24. doi: 10.1016/j.bbadis.2015.08.002. Epub 2015 Aug 4. Biochim Biophys Acta. 2015. PMID: 26248058 Free PMC article.

7

Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain.

Orr ME, Garbarino VR, Salinas A, Buffenstein R. Orr ME, et al. Front Neurosci. 2016 Nov 8;10:504. doi: 10.3389/fnins.2016.00504. eCollection 2016. Front Neurosci. 2016. PMID: 27877105 Free PMC article.

8

Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system.

Ramirez P, Zuniga G, Sun W, Beckmann A, Ochoa E, DeVos SL, Hyman B, Chiu G, Roy ER, Cao W, Orr M, Buggia-Prevot V, Ray WJ, Frost B. Ramirez P, et al. Prog Neurobiol. 2022 Jan;208:102181. doi: 10.1016/j.pneurobio.2021.102181. Epub 2021 Oct 17. Prog Neurobiol. 2022. PMID: 34670118 Free PMC article.

9

Biological aging processes underlying cognitive decline and neurodegenerative disease.

Gonzales MM, Garbarino VR, Pollet E, Palavicini JP, Kellogg DL Jr, Kraig E, Orr ME. Gonzales MM, et al. Among authors: orr me. J Clin Invest. 2022 May 16;132(10):e158453. doi: 10.1172/JCI158453. J Clin Invest. 2022. PMID: 35575089 Free PMC article. Review.

10

Tau protein aggregation is associated with cellular senescence in the brain.

Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME. Musi N, et al. Among authors: orr me. Aging Cell. 2018 Dec;17(6):e12840. doi: 10.1111/acel.12840. Epub 2018 Oct 11. Aging Cell. 2018. PMID: 30126037 Free PMC article.

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