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Health and population effects of rare gene knockouts in adult humans with related parents.
Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C, Bellary S, Bockett NA, Giorda K, Griffiths CJ, Hemingway H, Jia Z, Kelly MA, Khawaja HA, Lek M, McCarthy S, McEachan R, O'Donnell-Luria A, Paigen K, Parisinos CA, Sheridan E, Southgate L, Tee L, Thomas M, Xue Y, Schnall-Levin M, Petkov PM, Tyler-Smith C, Maher ER, Trembath RC, MacArthur DG, Wright J, Durbin R, van Heel DA. Narasimhan VM, et al. Among authors: baker cl. Science. 2016 Apr 22;352(6284):474-7. doi: 10.1126/science.aac8624. Epub 2016 Mar 3. Science. 2016. PMID: 26940866 Free PMC article.
Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage.
Walker M, Billings T, Baker CL, Powers N, Tian H, Saxl RL, Choi K, Hibbs MA, Carter GW, Handel MA, Paigen K, Petkov PM. Walker M, et al. Among authors: baker cl. Epigenetics Chromatin. 2015 Sep 7;8:31. doi: 10.1186/s13072-015-0024-6. eCollection 2015. Epigenetics Chromatin. 2015. PMID: 26351520 Free PMC article.
Tissue-Specific Trans Regulation of the Mouse Epigenome.
Baker CL, Walker M, Arat S, Ananda G, Petkova P, Powers NR, Tian H, Spruce C, Ji B, Rausch D, Choi K, Petkov PM, Carter GW, Paigen K. Baker CL, et al. Genetics. 2019 Mar;211(3):831-845. doi: 10.1534/genetics.118.301697. Epub 2018 Dec 28. Genetics. 2019. PMID: 30593494 Free PMC article.
Histone methyltransferase PRDM9 is not essential for meiosis in male mice.
Mihola O, Pratto F, Brick K, Linhartova E, Kobets T, Flachs P, Baker CL, Sedlacek R, Paigen K, Petkov PM, Camerini-Otero RD, Trachtulec Z. Mihola O, et al. Among authors: baker cl. Genome Res. 2019 Jul;29(7):1078-1086. doi: 10.1101/gr.244426.118. Epub 2019 Jun 11. Genome Res. 2019. PMID: 31186301 Free PMC article.
308 results