Shekhar TM - Search Results

1

Data on the DNA damaging and mutagenic potential of the BH3-mimetics ABT-263/Navitoclax and TW-37.

Green MM, Shekhar TM, Hawkins CJ. Green MM, et al. Among authors: shekhar tm. Data Brief. 2016 Jan 16;6:710-4. doi: 10.1016/j.dib.2016.01.013. eCollection 2016 Mar. Data Brief. 2016. PMID: 26958630 Free PMC article.

2

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells.

Shekhar TM, Green MM, Rayner DM, Miles MA, Cutts SM, Hawkins CJ. Shekhar TM, et al. Mutat Res. 2015 Jul;777:23-32. doi: 10.1016/j.mrfmmm.2015.04.005. Epub 2015 Apr 15. Mutat Res. 2015. PMID: 25916945

3

TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells.

Miles MA, Shekhar TM, Hall NE, Hawkins CJ. Miles MA, et al. Among authors: shekhar tm. Mutat Res. 2016 May;787:15-31. doi: 10.1016/j.mrfmmm.2016.02.006. Epub 2016 Feb 18. Mutat Res. 2016. PMID: 26943263

4

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα.

Shekhar TM, Miles MA, Gupte A, Taylor S, Tascone B, Walkley CR, Hawkins CJ. Shekhar TM, et al. Oncotarget. 2016 Jun 7;7(23):33866-86. doi: 10.18632/oncotarget.8980. Oncotarget. 2016. PMID: 27129149 Free PMC article.

5

Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in mice.

Shekhar TM, Burvenich IJG, Harris MA, Rigopoulos A, Zanker D, Spurling A, Parker BS, Walkley CR, Scott AM, Hawkins CJ. Shekhar TM, et al. BMC Cancer. 2019 Sep 14;19(1):924. doi: 10.1186/s12885-019-6103-5. BMC Cancer. 2019. PMID: 31521127 Free PMC article.

6

The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice.

Harris MA, Shekhar TM, Miles MA, Cerra C, Hawkins CJ. Harris MA, et al. Among authors: shekhar tm. Clin Exp Metastasis. 2021 Oct;38(5):441-449. doi: 10.1007/s10585-021-10116-9. Epub 2021 Aug 16. Clin Exp Metastasis. 2021. PMID: 34398333

7

Yeast techniques for modeling drugs targeting Bcl-2 and caspase family members.

Beaumont TE, Shekhar TM, Kaur L, Pantaki-Eimany D, Kvansakul M, Hawkins CJ. Beaumont TE, et al. Among authors: shekhar tm. Cell Death Dis. 2013 May 2;4(5):e619. doi: 10.1038/cddis.2013.143. Cell Death Dis. 2013. PMID: 23640461 Free PMC article.

8

Pre-clinical evaluation of proteasome inhibitors for canine and human osteosarcoma.

Patatsos K, Shekhar TM, Hawkins CJ. Patatsos K, et al. Among authors: shekhar tm. Vet Comp Oncol. 2018 Dec;16(4):544-553. doi: 10.1111/vco.12413. Epub 2018 Jul 12. Vet Comp Oncol. 2018. PMID: 29998615

9

Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice.

Harris MA, Hons B, Shekhar TM, Coupland LA, Miles MA, Hawkins CJ. Harris MA, et al. Among authors: shekhar tm. J Adolesc Young Adult Oncol. 2020 Dec;9(6):667-671. doi: 10.1089/jayao.2019.0172. Epub 2020 May 12. J Adolesc Young Adult Oncol. 2020. PMID: 32397787

10

The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice.

Harris MA, Miles MA, Shekhar TM, Cerra C, Georgy SR, Ryan SD, Cannon CM, Hawkins CJ. Harris MA, et al. Among authors: shekhar tm. Cancers (Basel). 2020 May 11;12(5):1207. doi: 10.3390/cancers12051207. Cancers (Basel). 2020. PMID: 32403415 Free PMC article.

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