Schurdak ME - Search Results

1

A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine.

Stern AM, Schurdak ME, Bahar I, Berg JM, Taylor DL. Stern AM, et al. Among authors: schurdak me. J Biomol Screen. 2016 Jul;21(6):521-34. doi: 10.1177/1087057116635818. Epub 2016 Mar 8. J Biomol Screen. 2016. PMID: 26962875 Free PMC article.

2

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery.

Gough AH, Chen N, Shun TY, Lezon TR, Boltz RC, Reese CE, Wagner J, Vernetti LA, Grandis JR, Lee AV, Stern AM, Schurdak ME, Taylor DL. Gough AH, et al. Among authors: schurdak me. PLoS One. 2014 Jul 18;9(7):e102678. doi: 10.1371/journal.pone.0102678. eCollection 2014. PLoS One. 2014. PMID: 25036749 Free PMC article.

3

Biologically Relevant Heterogeneity: Metrics and Practical Insights.

Gough A, Stern AM, Maier J, Lezon T, Shun TY, Chennubhotla C, Schurdak ME, Haney SA, Taylor DL. Gough A, et al. Among authors: schurdak me. SLAS Discov. 2017 Mar;22(3):213-237. doi: 10.1177/2472555216682725. Epub 2017 Jan 6. SLAS Discov. 2017. PMID: 28231035 Free PMC article. Review.

4

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington's Disease Model through the Application of Quantitative Systems Pharmacology.

Pei F, Li H, Henderson MJ, Titus SA, Jadhav A, Simeonov A, Cobanoglu MC, Mousavi SH, Shun T, McDermott L, Iyer P, Fioravanti M, Carlisle D, Friedlander RM, Bahar I, Taylor DL, Lezon TR, Stern AM, Schurdak ME. Pei F, et al. Among authors: schurdak me. Sci Rep. 2017 Dec 19;7(1):17803. doi: 10.1038/s41598-017-17378-y. Sci Rep. 2017. PMID: 29259176 Free PMC article.

5

Integrating Analysis of Cellular Heterogeneity in High-Content Dose-Response Studies.

Gough A, Shun TY, Taylor DL, Schurdak M. Gough A, et al. Methods Mol Biol. 2018;1745:25-46. doi: 10.1007/978-1-4939-7680-5_2. Methods Mol Biol. 2018. PMID: 29476461

6

A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.

Schurdak ME, Pei F, Lezon TR, Carlisle D, Friedlander R, Taylor DL, Stern AM. Schurdak ME, et al. Methods Mol Biol. 2018;1787:207-222. doi: 10.1007/978-1-4939-7847-2_16. Methods Mol Biol. 2018. PMID: 29736721

7

Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology.

Taylor DL, Gough A, Schurdak ME, Vernetti L, Chennubhotla CS, Lefever D, Pei F, Faeder JR, Lezon TR, Stern AM, Bahar I. Taylor DL, et al. Among authors: schurdak me. Handb Exp Pharmacol. 2019;260:327-367. doi: 10.1007/164_2019_239. Handb Exp Pharmacol. 2019. PMID: 31201557 Free PMC article.

8

Applications of the microphysiology systems database for experimental ADME-Tox and disease models.

Schurdak M, Vernetti L, Bergenthal L, Wolter QK, Shun TY, Karcher S, Taylor DL, Gough A. Schurdak M, et al. Lab Chip. 2020 Apr 14;20(8):1472-1492. doi: 10.1039/c9lc01047e. Lab Chip. 2020. PMID: 32211684 Free PMC article.

9

Targeting NAD⁺ Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance.

Jane EP, Premkumar DR, Thambireddy S, Golbourn B, Agnihotri S, Bertrand KC, Mack SC, Myers MI, Chattopadhyay A, Taylor DL, Schurdak ME, Stern AM, Pollack IF. Jane EP, et al. Among authors: schurdak me. Mol Cancer Res. 2020 Jul;18(7):1004-1017. doi: 10.1158/1541-7786.MCR-19-0669. Epub 2020 Apr 1. Mol Cancer Res. 2020. PMID: 32238439 Free PMC article.

10

Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS).

Sakolish C, Reese CE, Luo YS, Valdiviezo A, Schurdak ME, Gough A, Taylor DL, Chiu WA, Vernetti LA, Rusyn I. Sakolish C, et al. Among authors: schurdak me. Toxicology. 2021 Jan 30;448:152651. doi: 10.1016/j.tox.2020.152651. Epub 2020 Dec 8. Toxicology. 2021. PMID: 33307106 Free PMC article.

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