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A newly discovered protein export machine in malaria parasites.
de Koning-Ward TF, Gilson PR, Boddey JA, Rug M, Smith BJ, Papenfuss AT, Sanders PR, Lundie RJ, Maier AG, Cowman AF, Crabb BS. de Koning-Ward TF, et al. Among authors: boddey ja. Nature. 2009 Jun 18;459(7249):945-9. doi: 10.1038/nature08104. Nature. 2009. PMID: 19536257 Free PMC article.
An aspartyl protease directs malaria effector proteins to the host cell.
Boddey JA, Hodder AN, Günther S, Gilson PR, Patsiouras H, Kapp EA, Pearce JA, de Koning-Ward TF, Simpson RJ, Crabb BS, Cowman AF. Boddey JA, et al. Nature. 2010 Feb 4;463(7281):627-31. doi: 10.1038/nature08728. Nature. 2010. PMID: 20130643 Free PMC article.
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.
Sleebs BE, Lopaticki S, Marapana DS, O'Neill MT, Rajasekaran P, Gazdik M, Günther S, Whitehead LW, Lowes KN, Barfod L, Hviid L, Shaw PJ, Hodder AN, Smith BJ, Cowman AF, Boddey JA. Sleebs BE, et al. Among authors: boddey ja. PLoS Biol. 2014 Jul 1;12(7):e1001897. doi: 10.1371/journal.pbio.1001897. eCollection 2014 Jul. PLoS Biol. 2014. PMID: 24983235 Free PMC article.
54 results