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Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer.
Palmer DH, Mautner V, Mirza D, Oliff S, Gerritsen W, van der Sijp JR, Hubscher S, Reynolds G, Bonney S, Rajaratnam R, Hull D, Horne M, Ellis J, Mountain A, Hill S, Harris PA, Searle PF, Young LS, James ND, Kerr DJ. Palmer DH, et al. J Clin Oncol. 2004 May 1;22(9):1546-52. doi: 10.1200/JCO.2004.10.005. Epub 2004 Mar 29. J Clin Oncol. 2004. PMID: 15051757 Clinical Trial.
270 results