Iwanaga T - Search Results

1

Effects of topiroxostat and febuxostat on urinary albumin excretion and plasma xanthine oxidoreductase activity in db/db mice.

Nakamura T, Murase T, Nampei M, Morimoto N, Ashizawa N, Iwanaga T, Sakamoto R. Nakamura T, et al. Among authors: iwanaga t. Eur J Pharmacol. 2016 Jun 5;780:224-31. doi: 10.1016/j.ejphar.2016.03.055. Epub 2016 Mar 30. Eur J Pharmacol. 2016. PMID: 27038523

2

Design, synthesis, and pharmacological and pharmacokinetic evaluation of 3-phenyl-5-pyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors.

Sato T, Ashizawa N, Iwanaga T, Nakamura H, Matsumoto K, Inoue T, Nagata O. Sato T, et al. Among authors: iwanaga t. Bioorg Med Chem Lett. 2009 Jan 1;19(1):184-7. doi: 10.1016/j.bmcl.2008.10.122. Epub 2008 Nov 5. Bioorg Med Chem Lett. 2009. PMID: 19027292

3

FYX-051, a xanthine oxidoreductase inhibitor, induces nephropathy in rats, but not in monkeys.

Shimo T, Ashizawa N, Moto M, Matsumoto K, Iwanaga T, Nagata O. Shimo T, et al. Among authors: iwanaga t. Toxicol Pathol. 2009 Jun;37(4):438-45. doi: 10.1177/0192623309332995. Epub 2009 Mar 31. Toxicol Pathol. 2009. PMID: 19336671

4

Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected].

Sato T, Ashizawa N, Matsumoto K, Iwanaga T, Nakamura H, Inoue T, Nagata O. Sato T, et al. Among authors: iwanaga t. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6225-9. doi: 10.1016/j.bmcl.2009.08.091. Epub 2009 Sep 2. Bioorg Med Chem Lett. 2009. PMID: 19783139

5

Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.

Shimo T, Ashizawa N, Moto M, Iwanaga T, Nagata O. Shimo T, et al. Among authors: iwanaga t. Arch Toxicol. 2011 May;85(5):505-12. doi: 10.1007/s00204-010-0598-5. Epub 2010 Oct 10. Arch Toxicol. 2011. PMID: 20936465

6

Xanthine crystals induced by topiroxostat, a xanthine oxidoreductase inhibitor, in rats, cause transitional cell tumors.

Shimo T, Moto M, Ashizawa N, Matsumoto K, Iwanaga T, Saito K. Shimo T, et al. Among authors: iwanaga t. Arch Toxicol. 2014 Apr;88(4):1035-42. doi: 10.1007/s00204-014-1195-9. Epub 2014 Jan 22. Arch Toxicol. 2014. PMID: 24448833

7

Uricosuric agents decrease the plasma urate level in rats by concomitant treatment with topiroxostat, a novel xanthine oxidoreductase inhibitor.

Taniguchi T, Ashizawa N, Matsumoto K, Iwanaga T, Saitoh K. Taniguchi T, et al. Among authors: iwanaga t. J Pharm Pharmacol. 2016 Jan;68(1):76-83. doi: 10.1111/jphp.12490. Epub 2015 Nov 21. J Pharm Pharmacol. 2016. PMID: 26589240

8

Enhancement of pharmacological effects of uricosuric agents by concomitant treatment with pyrazinamide in rats.

Taniguchi T, Ashizawa N, Matsumoto K, Iwanaga T. Taniguchi T, et al. Among authors: iwanaga t. Naunyn Schmiedebergs Arch Pharmacol. 2017 Mar;390(3):253-260. doi: 10.1007/s00210-016-1324-5. Epub 2016 Dec 8. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 27933340

9

Novel bisphosphonate compound FYB-931 preferentially inhibits aortic calcification in vitamin D3-treated rats.

Ishida K, Ashizawa N, Matsumoto K, Kobashi S, Kurita N, Shigematsu T, Iwanaga T. Ishida K, et al. Among authors: iwanaga t. J Bone Miner Metab. 2019 Sep;37(5):796-804. doi: 10.1007/s00774-019-00987-0. Epub 2019 Feb 2. J Bone Miner Metab. 2019. PMID: 30712064

10

Pharmacological Evaluation of Dotinurad, a Selective Urate Reabsorption Inhibitor.

Taniguchi T, Ashizawa N, Matsumoto K, Saito R, Motoki K, Sakai M, Chikamatsu N, Hagihara C, Hashiba M, Iwanaga T. Taniguchi T, et al. Among authors: iwanaga t. J Pharmacol Exp Ther. 2019 Oct;371(1):162-170. doi: 10.1124/jpet.119.259341. Epub 2019 Aug 1. J Pharmacol Exp Ther. 2019. PMID: 31371478

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