Di Ianni L - Search Results

1

Lactate dehydrogenase inhibition: exploring possible applications beyond cancer treatment.

Di Stefano G, Manerba M, Di Ianni L, Fiume L. Di Stefano G, et al. Among authors: di ianni l. Future Med Chem. 2016 Apr;8(6):713-25. doi: 10.4155/fmc.16.10. Epub 2016 Apr 7. Future Med Chem. 2016. PMID: 27054686 Review.

2

Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes.

Manerba M, Di Ianni L, Fiume L, Roberti M, Recanatini M, Di Stefano G. Manerba M, et al. Among authors: di ianni l. Eur J Pharm Sci. 2015 Jul 10;74:95-102. doi: 10.1016/j.ejps.2015.04.022. Epub 2015 Apr 28. Eur J Pharm Sci. 2015. PMID: 25930121

3

Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.

Rupiani S, Buonfiglio R, Manerba M, Di Ianni L, Vettraino M, Giacomini E, Masetti M, Falchi F, Di Stefano G, Roberti M, Recanatini M. Rupiani S, et al. Among authors: di ianni l. Eur J Med Chem. 2015 Aug 28;101:63-70. doi: 10.1016/j.ejmech.2015.06.028. Epub 2015 Jun 18. Eur J Med Chem. 2015. PMID: 26114812

4

Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells.

Manerba M, Di Ianni L, Govoni M, Roberti M, Recanatini M, Di Stefano G. Manerba M, et al. Among authors: di ianni l. Eur J Pharm Sci. 2017 Jan 1;96:37-44. doi: 10.1016/j.ejps.2016.09.014. Epub 2016 Sep 10. Eur J Pharm Sci. 2017. PMID: 27622920

5

Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.

Rupiani S, Guidotti L, Manerba M, Di Ianni L, Giacomini E, Falchi F, Di Stefano G, Roberti M, Recanatini M. Rupiani S, et al. Among authors: di ianni l. Org Biomol Chem. 2016 Nov 22;14(46):10981-10987. doi: 10.1039/c6ob01977c. Org Biomol Chem. 2016. PMID: 27827510

6

The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells.

Manerba M, Di Ianni L, Govoni M, Comparone A, Di Stefano G. Manerba M, et al. Among authors: di ianni l. PLoS One. 2018 Aug 23;13(8):e0202588. doi: 10.1371/journal.pone.0202588. eCollection 2018. PLoS One. 2018. PMID: 30138330 Free PMC article.

7

LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells.

Manerba M, Di Ianni L, Govoni M, Roberti M, Recanatini M, Di Stefano G. Manerba M, et al. Among authors: di ianni l. Eur J Pharm Sci. 2017 Jul 15;105:91-98. doi: 10.1016/j.ejps.2017.05.015. Epub 2017 May 10. Eur J Pharm Sci. 2017. PMID: 28501492

8

Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors.

Falchi F, Giacomini E, Masini T, Boutard N, Di Ianni L, Manerba M, Farabegoli F, Rossini L, Robertson J, Minucci S, Pallavicini I, Di Stefano G, Roberti M, Pellicciari R, Cavalli A. Falchi F, et al. Among authors: di ianni l. ACS Chem Biol. 2017 Oct 20;12(10):2491-2497. doi: 10.1021/acschembio.7b00707. Epub 2017 Sep 1. ACS Chem Biol. 2017. PMID: 28841282 Free article.

9

Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.

Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M. Ždralević M, et al. Among authors: di ianni l. J Biol Chem. 2018 Oct 12;293(41):15947-15961. doi: 10.1074/jbc.RA118.004180. Epub 2018 Aug 29. J Biol Chem. 2018. PMID: 30158244 Free PMC article.

10

A nanobody targeting the translocated intimin receptor inhibits the attachment of enterohemorrhagic E. coli to human colonic mucosa.

Ruano-Gallego D, Yara DA, Di Ianni L, Frankel G, Schüller S, Fernández LÁ. Ruano-Gallego D, et al. Among authors: di ianni l. PLoS Pathog. 2019 Aug 29;15(8):e1008031. doi: 10.1371/journal.ppat.1008031. eCollection 2019 Aug. PLoS Pathog. 2019. PMID: 31465434 Free PMC article.

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