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Page 1
Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.
Juss JK, House D, Amour A, Begg M, Herre J, Storisteanu DM, Hoenderdos K, Bradley G, Lennon M, Summers C, Hessel EM, Condliffe A, Chilvers ER. Juss JK, et al. Among authors: hoenderdos k. Am J Respir Crit Care Med. 2016 Oct 15;194(8):961-973. doi: 10.1164/rccm.201509-1818OC. Am J Respir Crit Care Med. 2016. PMID: 27064380 Free PMC article.
Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
Li W, Long L, Yang X, Tong Z, Southwood M, King R, Caruso P, Upton PD, Yang P, Bocobo GA, Nikolic I, Higuera A, Salmon RM, Jiang H, Lodge KM, Hoenderdos K, Baron RM, Yu PB, Condliffe AM, Summers C, Nourshargh S, Chilvers ER, Morrell NW. Li W, et al. Among authors: hoenderdos k. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1419-1430. doi: 10.1164/rccm.202005-1761OC. Am J Respir Crit Care Med. 2021. PMID: 33320799 Free PMC article.
Hypoxia upregulates neutrophil degranulation and potential for tissue injury.
Hoenderdos K, Lodge KM, Hirst RA, Chen C, Palazzo SG, Emerenciana A, Summers C, Angyal A, Porter L, Juss JK, O'Callaghan C, Chilvers ER, Condliffe AM. Hoenderdos K, et al. Thorax. 2016 Nov;71(11):1030-1038. doi: 10.1136/thoraxjnl-2015-207604. Epub 2016 Aug 31. Thorax. 2016. PMID: 27581620 Free PMC article.
NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
Sowerby JM, Thomas DC, Clare S, Espéli M, Guerrero JA, Hoenderdos K, Harcourt K, Marsden M, Abdul-Karim J, Clement M, Antrobus R, Umrania Y, Barton PR, Flint SM, Juss JK, Condliffe AM, Lyons PA, Humphreys IR, Chilvers ER, Ouwehand WH, Dougan G, Smith KG. Sowerby JM, et al. Among authors: hoenderdos k. J Clin Invest. 2017 Sep 1;127(9):3521-3526. doi: 10.1172/JCI91684. Epub 2017 Aug 7. J Clin Invest. 2017. PMID: 28783043 Free PMC article.
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity.
Thomas DC, Clare S, Sowerby JM, Pardo M, Juss JK, Goulding DA, van der Weyden L, Storisteanu D, Prakash A, Espéli M, Flint S, Lee JC, Hoenderdos K, Kane L, Harcourt K, Mukhopadhyay S, Umrania Y, Antrobus R, Nathan JA, Adams DJ, Bateman A, Choudhary JS, Lyons PA, Condliffe AM, Chilvers ER, Dougan G, Smith KG. Thomas DC, et al. Among authors: hoenderdos k. J Exp Med. 2017 Apr 3;214(4):1111-1128. doi: 10.1084/jem.20161382. Epub 2017 Mar 28. J Exp Med. 2017. PMID: 28351984 Free PMC article.