Cobb LJ - Search Results

1

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers.

Cobb LJ, Lee C, Xiao J, Yen K, Wong RG, Nakamura HK, Mehta HH, Gao Q, Ashur C, Huffman DM, Wan J, Muzumdar R, Barzilai N, Cohen P. Cobb LJ, et al. Aging (Albany NY). 2016 Apr;8(4):796-809. doi: 10.18632/aging.100943. Aging (Albany NY). 2016. PMID: 27070352 Free PMC article.

2

Phosphorylation by DNA-dependent protein kinase is critical for apoptosis induction by insulin-like growth factor binding protein-3.

Cobb LJ, Liu B, Lee KW, Cohen P. Cobb LJ, et al. Cancer Res. 2006 Nov 15;66(22):10878-84. doi: 10.1158/0008-5472.CAN-06-0585. Cancer Res. 2006. PMID: 17108124

3

Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation.

Cobb LJ, Mehta H, Cohen P. Cobb LJ, et al. Mol Endocrinol. 2009 Oct;23(10):1624-33. doi: 10.1210/me.2008-0365. Epub 2009 Jun 25. Mol Endocrinol. 2009. PMID: 19556345 Free PMC article.

4

Humanin: a novel central regulator of peripheral insulin action.

Muzumdar RH, Huffman DM, Atzmon G, Buettner C, Cobb LJ, Fishman S, Budagov T, Cui L, Einstein FH, Poduval A, Hwang D, Barzilai N, Cohen P. Muzumdar RH, et al. Among authors: cobb lj. PLoS One. 2009 Jul 22;4(7):e6334. doi: 10.1371/journal.pone.0006334. PLoS One. 2009. PMID: 19623253 Free PMC article.

5

Pomegranate extract induces apoptosis in human prostate cancer cells by modulation of the IGF-IGFBP axis.

Koyama S, Cobb LJ, Mehta HH, Seeram NP, Heber D, Pantuck AJ, Cohen P. Koyama S, et al. Among authors: cobb lj. Growth Horm IGF Res. 2010 Feb;20(1):55-62. doi: 10.1016/j.ghir.2009.09.003. Epub 2009 Oct 22. Growth Horm IGF Res. 2010. PMID: 19853487 Free PMC article.

6

Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis.

Lue Y, Swerdloff R, Liu Q, Mehta H, Hikim AS, Lee KW, Jia Y, Hwang D, Cobb LJ, Cohen P, Wang C. Lue Y, et al. Among authors: cobb lj. Endocrinology. 2010 Jan;151(1):350-7. doi: 10.1210/en.2009-0577. Epub 2009 Dec 1. Endocrinology. 2010. PMID: 19952275

7

Pharmacokinetics and tissue distribution of humanin and its analogues in male rodents.

Chin YP, Keni J, Wan J, Mehta H, Anene F, Jia Y, Lue YH, Swerdloff R, Cobb LJ, Wang C, Cohen P. Chin YP, et al. Among authors: cobb lj. Endocrinology. 2013 Oct;154(10):3739-44. doi: 10.1210/en.2012-2004. Epub 2013 Jul 8. Endocrinology. 2013. PMID: 23836030 Free PMC article.

8

The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice.

Hoang PT, Park P, Cobb LJ, Paharkova-Vatchkova V, Hakimi M, Cohen P, Lee KW. Hoang PT, et al. Among authors: cobb lj. Metabolism. 2010 Mar;59(3):343-9. doi: 10.1016/j.metabol.2009.08.001. Epub 2009 Oct 1. Metabolism. 2010. PMID: 19800083 Free PMC article.

9

IGFBP-3 is a metastasis suppression gene in prostate cancer.

Mehta HH, Gao Q, Galet C, Paharkova V, Wan J, Said J, Sohn JJ, Lawson G, Cohen P, Cobb LJ, Lee KW. Mehta HH, et al. Among authors: cobb lj. Cancer Res. 2011 Aug 1;71(15):5154-63. doi: 10.1158/0008-5472.CAN-10-4513. Epub 2011 Jun 22. Cancer Res. 2011. PMID: 21697285 Free PMC article.

10

The cytoprotective peptide humanin is induced and neutralizes Bax after pro-apoptotic stress in the rat testis.

Jia Y, Lue YH, Swerdloff R, Lee KW, Cobb LJ, Cohen P, Wang C. Jia Y, et al. Among authors: cobb lj. Andrology. 2013 Jul;1(4):651-9. doi: 10.1111/j.2047-2927.2013.00091.x. Epub 2013 May 20. Andrology. 2013. PMID: 23686888 Free PMC article.

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