Zannettino AC - Search Results

1

Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.

Walia MK, Ho PM, Taylor S, Ng AJ, Gupte A, Chalk AM, Zannettino AC, Martin TJ, Walkley CR. Walia MK, et al. Among authors: zannettino ac. Elife. 2016 Apr 12;5:e13446. doi: 10.7554/eLife.13446. Elife. 2016. PMID: 27070462 Free PMC article.

2

Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation.

Martin SK, Fitter S, Dutta AK, Matthews MP, Walkley CR, Hall MN, Ruegg MA, Gronthos S, Zannettino AC. Martin SK, et al. Among authors: zannettino ac. Stem Cells. 2015 Apr;33(4):1359-65. doi: 10.1002/stem.1931. Stem Cells. 2015. PMID: 25537496

3

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: zannettino ac. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.

4

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.

Baker EK, Taylor S, Gupte A, Sharp PP, Walia M, Walsh NC, Zannettino AC, Chalk AM, Burns CJ, Walkley CR. Baker EK, et al. Among authors: zannettino ac. Sci Rep. 2015 May 6;5:10120. doi: 10.1038/srep10120. Sci Rep. 2015. PMID: 25944566 Free PMC article.

5

Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death.

Bhattacharya S, Chalk AM, Ng AJ, Martin TJ, Zannettino AC, Purton LE, Lu J, Baker EK, Walkley CR. Bhattacharya S, et al. Among authors: zannettino ac. Oncogene. 2016 Oct 6;35(40):5282-5294. doi: 10.1038/onc.2016.68. Epub 2016 Apr 4. Oncogene. 2016. PMID: 27041566

6

Loss of ephrinB1 in osteogenic progenitor cells impedes endochondral ossification and compromises bone strength integrity during skeletal development.

Nguyen TM, Arthur A, Paton S, Hemming S, Panagopoulos R, Codrington J, Walkley CR, Zannettino AC, Gronthos S. Nguyen TM, et al. Among authors: zannettino ac. Bone. 2016 Dec;93:12-21. doi: 10.1016/j.bone.2016.09.009. Epub 2016 Sep 10. Bone. 2016. PMID: 27622886

7

mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation.

Fitter S, Matthews MP, Martin SK, Xie J, Ooi SS, Walkley CR, Codrington JD, Ruegg MA, Hall MN, Proud CG, Gronthos S, Zannettino ACW. Fitter S, et al. Mol Cell Biol. 2017 Mar 17;37(7):e00668-16. doi: 10.1128/MCB.00668-16. Print 2017 Apr 1. Mol Cell Biol. 2017. PMID: 28069737 Free PMC article.

8

mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis.

Martin SK, Fitter S, El Khawanky N, Grose RH, Walkley CR, Purton LE, Ruegg MA, Hall MN, Gronthos S, Zannettino ACW. Martin SK, et al. Sci Rep. 2018 Sep 28;8(1):14501. doi: 10.1038/s41598-018-32858-5. Sci Rep. 2018. PMID: 30266921 Free PMC article.

9

Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo.

Zinonos I, Labrinidis A, Lee M, Liapis V, Hay S, Ponomarev V, Diamond P, Findlay DM, Zannettino AC, Evdokiou A. Zinonos I, et al. Among authors: zannettino ac. J Bone Miner Res. 2011 Mar;26(3):630-43. doi: 10.1002/jbmr.244. J Bone Miner Res. 2011. PMID: 20818644 Free PMC article.

10

Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.

Liapis V, Labrinidis A, Zinonos I, Hay S, Ponomarev V, Panagopoulos V, DeNichilo M, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Liapis V, et al. Cancer Lett. 2015 Feb 1;357(1):160-169. doi: 10.1016/j.canlet.2014.11.020. Epub 2014 Nov 15. Cancer Lett. 2015. PMID: 25444931 Free PMC article.

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