Webster SP - Search Results

1

Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback.

Wilson K, Auer M, Binnie M, Zheng X, Pham NT, Iredale JP, Webster SP, Mole DJ. Wilson K, et al. Among authors: webster sp. Cell Death Dis. 2016 Apr 14;7(4):e2197. doi: 10.1038/cddis.2016.87. Cell Death Dis. 2016. PMID: 27077813 Free PMC article.

2

Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

Webster SP, Ward P, Binnie M, Craigie E, McConnell KM, Sooy K, Vinter A, Seckl JR, Walker BR. Webster SP, et al. Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. doi: 10.1016/j.bmcl.2007.02.057. Epub 2007 Feb 25. Bioorg Med Chem Lett. 2007. PMID: 17350260

3

Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.

Webster SP, Binnie M, McConnell KM, Sooy K, Ward P, Greaney MF, Vinter A, Pallin TD, Dyke HJ, Gill MI, Warner I, Seckl JR, Walker BR. Webster SP, et al. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3265-71. doi: 10.1016/j.bmcl.2010.04.055. Epub 2010 Apr 18. Bioorg Med Chem Lett. 2010. PMID: 20452767 Free PMC article.

4

Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice.

Sooy K, Webster SP, Noble J, Binnie M, Walker BR, Seckl JR, Yau JL. Sooy K, et al. Among authors: webster sp. J Neurosci. 2010 Oct 13;30(41):13867-72. doi: 10.1523/JNEUROSCI.2783-10.2010. J Neurosci. 2010. PMID: 20943927 Free PMC article.

5

Bacterial expression of human kynurenine 3-monooxygenase: solubility, activity, purification.

Wilson K, Mole DJ, Binnie M, Homer NZ, Zheng X, Yard BA, Iredale JP, Auer M, Webster SP. Wilson K, et al. Among authors: webster sp. Protein Expr Purif. 2014 Mar;95(100):96-103. doi: 10.1016/j.pep.2013.11.015. Epub 2013 Dec 4. Protein Expr Purif. 2014. PMID: 24316190 Free PMC article.

6

Lead discovery for human kynurenine 3-monooxygenase by high-throughput RapidFire mass spectrometry.

Lowe DM, Gee M, Haslam C, Leavens B, Christodoulou E, Hissey P, Hardwicke P, Argyrou A, Webster SP, Mole DJ, Wilson K, Binnie M, Yard BA, Dean T, Liddle J, Uings I, Hutchinson JP. Lowe DM, et al. Among authors: webster sp. J Biomol Screen. 2014 Apr;19(4):508-15. doi: 10.1177/1087057113518069. Epub 2013 Dec 31. J Biomol Screen. 2014. PMID: 24381207

7

A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery.

Wilson K, Mole DJ, Homer NZ, Iredale JP, Auer M, Webster SP. Wilson K, et al. Among authors: webster sp. J Biomol Screen. 2015 Feb;20(2):292-8. doi: 10.1177/1087057114554171. Epub 2014 Oct 8. J Biomol Screen. 2015. PMID: 25296660

8

UFSRAT: Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1.

Shave S, Blackburn EA, Adie J, Houston DR, Auer M, Webster SP, Taylor P, Walkinshaw MD. Shave S, et al. Among authors: webster sp. PLoS One. 2015 Feb 6;10(2):e0116570. doi: 10.1371/journal.pone.0116570. eCollection 2015. PLoS One. 2015. PMID: 25659145 Free PMC article.

9

Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.

Sooy K, Noble J, McBride A, Binnie M, Yau JL, Seckl JR, Walker BR, Webster SP. Sooy K, et al. Among authors: webster sp. Endocrinology. 2015 Dec;156(12):4592-603. doi: 10.1210/en.2015-1395. Epub 2015 Aug 25. Endocrinology. 2015. PMID: 26305888 Free PMC article.

10

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold.

Leiva R, Seira C, McBride A, Binnie M, Luque FJ, Bidon-Chanal A, Webster SP, Vázquez S. Leiva R, et al. Among authors: webster sp. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4250-3. doi: 10.1016/j.bmcl.2015.07.097. Epub 2015 Aug 5. Bioorg Med Chem Lett. 2015. PMID: 26306982 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

66 results

Search Page

Filters