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Page 1
Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor.
Gustafsson R, Jemth AS, Gustafsson NM, Färnegårdh K, Loseva O, Wiita E, Bonagas N, Dahllund L, Llona-Minguez S, Häggblad M, Henriksson M, Andersson Y, Homan E, Helleday T, Stenmark P. Gustafsson R, et al. Among authors: dahllund l. Cancer Res. 2017 Feb 15;77(4):937-948. doi: 10.1158/0008-5472.CAN-16-1476. Epub 2016 Nov 29. Cancer Res. 2017. PMID: 27899380
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Bonagas N, Gustafsson NMS, Henriksson M, Marttila P, Gustafsson R, Wiita E, Borhade S, Green AC, Vallin KSA, Sarno A, Svensson R, Göktürk C, Pham T, Jemth AS, Loseva O, Cookson V, Kiweler N, Sandberg L, Rasti A, Unterlass JE, Haraldsson M, Andersson Y, Scaletti ER, Bengtsson C, Paulin CBJ, Sanjiv K, Abdurakhmanov E, Pudelko L, Kunz B, Desroses M, Iliev P, Färnegårdh K, Krämer A, Garg N, Michel M, Häggblad S, Jarvius M, Kalderén C, Jensen AB, Almlöf I, Karsten S, Zhang SM, Häggblad M, Eriksson A, Liu J, Glinghammar B, Nekhotiaeva N, Klingegård F, Koolmeister T, Martens U, Llona-Minguez S, Moulson R, Nordström H, Parrow V, Dahllund L, Sjöberg B, Vargas IL, Vo DD, Wannberg J, Knapp S, Krokan HE, Arvidsson PI, Scobie M, Meiser J, Stenmark P, Berglund UW, Homan EJ, Helleday T. Bonagas N, et al. Among authors: dahllund l. Nat Cancer. 2022 Feb;3(2):156-172. doi: 10.1038/s43018-022-00331-y. Epub 2022 Feb 28. Nat Cancer. 2022. PMID: 35228749 Free PMC article.
Fed-batch production assessment of a tetravalent bispecific antibody: A case study on piggyBac stably transfected HEK293 cells.
Napoleone A, Laurén I, Linkgreim T, Dahllund L, Persson H, Andersson O, Olsson A, Hultqvist G, Frank P, Hall M, Morrison A, Andersson A, Lord M, Mangsbo S. Napoleone A, et al. Among authors: dahllund l. N Biotechnol. 2021 Nov 25;65:9-19. doi: 10.1016/j.nbt.2021.07.002. Epub 2021 Jul 15. N Biotechnol. 2021. PMID: 34273575 Free article.
A stop codon mutation in SCN9A causes lack of pain sensation.
Ahmad S, Dahllund L, Eriksson AB, Hellgren D, Karlsson U, Lund PE, Meijer IA, Meury L, Mills T, Moody A, Morinville A, Morten J, O'donnell D, Raynoschek C, Salter H, Rouleau GA, Krupp JJ. Ahmad S, et al. Among authors: dahllund l. Hum Mol Genet. 2007 Sep 1;16(17):2114-21. doi: 10.1093/hmg/ddm160. Epub 2007 Jun 27. Hum Mol Genet. 2007. PMID: 17597096
A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice.
Mebrahtu A, Laurén I, Veerman R, Akpinar GG, Lord M, Kostakis A, Astorga-Wells J, Dahllund L, Olsson A, Andersson O, Persson J, Persson H, Dönnes P, Rockberg J, Mangsbo S. Mebrahtu A, et al. Among authors: dahllund l. Nat Commun. 2024 Nov 5;15(1):9542. doi: 10.1038/s41467-024-53839-5. Nat Commun. 2024. PMID: 39500897 Free PMC article.
Local gene expression changes after UV-irradiation of human skin.
Weinkauf B, Rukwied R, Quiding H, Dahllund L, Johansson P, Schmelz M. Weinkauf B, et al. Among authors: dahllund l. PLoS One. 2012;7(6):e39411. doi: 10.1371/journal.pone.0039411. Epub 2012 Jun 22. PLoS One. 2012. PMID: 22761785 Free PMC article.
Mapping of tissue tropism determinants in coxsackievirus genomes.
Harvala H, Kalimo H, Dahllund L, Santti J, Hughes P, Hyypiä T, Stanway G. Harvala H, et al. Among authors: dahllund l. J Gen Virol. 2002 Jul;83(Pt 7):1697-1706. doi: 10.1099/0022-1317-83-7-1697. J Gen Virol. 2002. PMID: 12075089
12 results