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11 results

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Page 1
CYP2C75-involved autoinduction of metabolism in rhesus monkeys of methyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluoroacetyl)amino]cyclopropyl}carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate (MK-0686), a bradykinin B1 receptor antagonist.
Tang C, Carr BA, Poignant F, Ma B, Polsky-Fisher SL, Kuo Y, Strong-Basalyga K, Norcross A, Richards K, Eisenhandler R, Carlini EJ, Di Marco CN, Kuduk SD, Yu NX, Raab CE, Rushmore T, Frederick CB, Bock MG, Prueksaritanont T. Tang C, et al. Among authors: eisenhandler r. J Pharmacol Exp Ther. 2008 Jun;325(3):935-46. doi: 10.1124/jpet.107.136044. Epub 2008 Feb 29. J Pharmacol Exp Ther. 2008. PMID: 18310472
siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.
Burke RS, Somasuntharam I, Rearden P, Brown D, Deshmukh SV, DiPietro MA, DiMuzio J, Eisenhandler R, Fauty SE, Gibson C, Gindy ME, Hamilton KA, Knemeyer I, Koeplinger KA, Kwon HW, Lifsted TQ, Menzel K, Patel M, Pudvah N, Rudd DJ, Seitzer J, Strapps WR, Prueksaritanont T, Thompson CD, Hochman JH, Carr BA. Burke RS, et al. Among authors: eisenhandler r. Pharm Res. 2014 Dec;31(12):3445-60. doi: 10.1007/s11095-014-1433-0. Epub 2014 Jul 1. Pharm Res. 2014. PMID: 24980206
Pharmacokinetics of famotidine in infants.
Wenning LA, Murphy MG, James LP, Blumer JL, Marshall JD, Baier J, Scheimann AO, Panebianco DL, Zhong L, Eisenhandler R, Yeh KC, Kearns GL. Wenning LA, et al. Among authors: eisenhandler r. Clin Pharmacokinet. 2005;44(4):395-406. doi: 10.2165/00003088-200544040-00004. Clin Pharmacokinet. 2005. PMID: 15828852 Clinical Trial.
Lack of a clinically meaningful pharmacokinetic effect of rifabutin on raltegravir: in vitro/in vivo correlation.
Brainard DM, Kassahun K, Wenning LA, Petry AS, Liu C, Lunceford J, Hariparsad N, Eisenhandler R, Norcross A, DeNoia EP, Stone JA, Wagner JA, Iwamoto M. Brainard DM, et al. Among authors: eisenhandler r. J Clin Pharmacol. 2011 Jun;51(6):943-50. doi: 10.1177/0091270010375959. Epub 2010 Sep 17. J Clin Pharmacol. 2011. PMID: 20852006 Clinical Trial.
Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse.
Booth-Genthe CL, Louie SW, Carlini EJ, Li B, Leake BF, Eisenhandler R, Hochman JH, Mei Q, Kim RB, Rushmore TH, Yamazaki M. Booth-Genthe CL, et al. Among authors: eisenhandler r. J Pharmacol Toxicol Methods. 2006 Jul-Aug;54(1):78-89. doi: 10.1016/j.vascn.2005.12.004. Epub 2006 Mar 20. J Pharmacol Toxicol Methods. 2006. PMID: 16545584
High-throughput simultaneous determination of the HIV protease inhibitors indinavir and L-756423 in human plasma using semi-automated 96-well solid phase extraction and LC-MS/MS.
Rose MJ, Merschman SA, Eisenhandler R, Woolf EJ, Yeh KC, Lin L, Fang W, Hsieh J, Braun MP, Gatto GJ, Matuszewski BK. Rose MJ, et al. Among authors: eisenhandler r. J Pharm Biomed Anal. 2000 Dec 15;24(2):291-305. doi: 10.1016/s0731-7085(00)00420-9. J Pharm Biomed Anal. 2000. PMID: 11130208
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