Williams RL - Search Results

1

Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway.

Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Ziemba BP, et al. Among authors: williams rl. Biophys J. 2016 Apr 26;110(8):1811-1825. doi: 10.1016/j.bpj.2016.03.001. Biophys J. 2016. PMID: 27119641 Free PMC article.

2

Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α.

Burke JE, Vadas O, Berndt A, Finegan T, Perisic O, Williams RL. Burke JE, et al. Among authors: williams rl. Structure. 2011 Aug 10;19(8):1127-37. doi: 10.1016/j.str.2011.06.003. Structure. 2011. PMID: 21827948 Free PMC article.

3

Structural basis for activation and inhibition of class I phosphoinositide 3-kinases.

Vadas O, Burke JE, Zhang X, Berndt A, Williams RL. Vadas O, et al. Among authors: williams rl. Sci Signal. 2011 Oct 18;4(195):re2. doi: 10.1126/scisignal.2002165. Sci Signal. 2011. PMID: 22009150 Review.

4

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA).

Burke JE, Perisic O, Masson GR, Vadas O, Williams RL. Burke JE, et al. Among authors: williams rl. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15259-64. doi: 10.1073/pnas.1205508109. Epub 2012 Sep 4. Proc Natl Acad Sci U S A. 2012. PMID: 22949682 Free PMC article.

5

Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS).

Burke JE, Williams RL. Burke JE, et al. Among authors: williams rl. Adv Biol Regul. 2013 Jan;53(1):97-110. doi: 10.1016/j.jbior.2012.09.005. Epub 2012 Sep 13. Adv Biol Regul. 2013. PMID: 23194976 Free PMC article.

6

G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness.

Dbouk HA, Vadas O, Shymanets A, Burke JE, Salamon RS, Khalil BD, Barrett MO, Waldo GL, Surve C, Hsueh C, Perisic O, Harteneck C, Shepherd PR, Harden TK, Smrcka AV, Taussig R, Bresnick AR, Nürnberg B, Williams RL, Backer JM. Dbouk HA, et al. Among authors: williams rl. Sci Signal. 2012 Dec 4;5(253):ra89. doi: 10.1126/scisignal.2003264. Sci Signal. 2012. PMID: 23211529 Free PMC article.

7

Allosteric activation of PI3Kα by oncogenic mutations.

Burke JE, Perisic O, Williams RL. Burke JE, et al. Among authors: williams rl. Oncotarget. 2013 Feb;4(2):180-1. doi: 10.18632/oncotarget.913. Oncotarget. 2013. PMID: 23563630 Free PMC article. No abstract available.

8

Connecting with an old partner in a new way.

Burke JE, Williams RL. Burke JE, et al. Among authors: williams rl. Cancer Cell. 2013 May 13;23(5):559-61. doi: 10.1016/j.ccr.2013.04.023. Cancer Cell. 2013. PMID: 23680139 Free article.

9

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.

Walser R, Burke JE, Gogvadze E, Bohnacker T, Zhang X, Hess D, Küenzi P, Leitges M, Hirsch E, Williams RL, Laffargue M, Wymann MP. Walser R, et al. Among authors: williams rl. PLoS Biol. 2013;11(6):e1001587. doi: 10.1371/journal.pbio.1001587. Epub 2013 Jun 25. PLoS Biol. 2013. PMID: 23824069 Free PMC article.

10

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi.

D'Angelo G, Uemura T, Chuang CC, Polishchuk E, Santoro M, Ohvo-Rekilä H, Sato T, Di Tullio G, Varriale A, D'Auria S, Daniele T, Capuani F, Johannes L, Mattjus P, Monti M, Pucci P, Williams RL, Burke JE, Platt FM, Harada A, De Matteis MA. D'Angelo G, et al. Among authors: williams rl. Nature. 2013 Sep 5;501(7465):116-20. doi: 10.1038/nature12423. Epub 2013 Aug 4. Nature. 2013. PMID: 23913272

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