D'Amico D - Search Results

1

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.

Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D'Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J. Zhang H, et al. Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126/science.aaf2693. Epub 2016 Apr 28. Science. 2016. PMID: 27127236

2

Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons.

Zheng L, Bernard-Marissal N, Moullan N, D'Amico D, Auwerx J, Moore DJ, Knott G, Aebischer P, Schneider BL. Zheng L, et al. Hum Mol Genet. 2017 Feb 1;26(3):582-598. doi: 10.1093/hmg/ddw418. Hum Mol Genet. 2017. PMID: 28053050

3

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J. Quirós PM, et al. J Cell Biol. 2017 Jul 3;216(7):2027-2045. doi: 10.1083/jcb.201702058. Epub 2017 May 31. J Cell Biol. 2017. PMID: 28566324 Free PMC article.

4

Cytosolic Proteostasis Networks of the Mitochondrial Stress Response.

D'Amico D, Sorrentino V, Auwerx J. D'Amico D, et al. Trends Biochem Sci. 2017 Sep;42(9):712-725. doi: 10.1016/j.tibs.2017.05.002. Epub 2017 Jun 1. Trends Biochem Sci. 2017. PMID: 28579074 Review.

5

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.

Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J. Sorrentino V, et al. Nature. 2017 Dec 14;552(7684):187-193. doi: 10.1038/nature25143. Epub 2017 Dec 6. Nature. 2017. PMID: 29211722 Free PMC article.

6

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.

D'Amico D, Mottis A, Potenza F, Sorrentino V, Li H, Romani M, Lemos V, Schoonjans K, Zamboni N, Knott G, Schneider BL, Auwerx J. D'Amico D, et al. Mol Cell. 2019 Feb 21;73(4):775-787.e10. doi: 10.1016/j.molcel.2018.11.034. Epub 2019 Jan 11. Mol Cell. 2019. PMID: 30642763 Free PMC article.

7

Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy.

Luan P, D'Amico D, Andreux PA, Laurila PP, Wohlwend M, Li H, Imamura de Lima T, Place N, Rinsch C, Zanou N, Auwerx J. Luan P, et al. Sci Transl Med. 2021 Apr 7;13(588):eabb0319. doi: 10.1126/scitranslmed.abb0319. Sci Transl Med. 2021. PMID: 33827972

8

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.

D'Amico D, Andreux PA, Valdés P, Singh A, Rinsch C, Auwerx J. D'Amico D, et al. Trends Mol Med. 2021 Jul;27(7):687-699. doi: 10.1016/j.molmed.2021.04.009. Epub 2021 May 21. Trends Mol Med. 2021. PMID: 34030963 Free article. Review.

9

Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population.

Singh A, D'Amico D, Andreux PA, Dunngalvin G, Kern T, Blanco-Bose W, Auwerx J, Aebischer P, Rinsch C. Singh A, et al. Eur J Clin Nutr. 2022 Feb;76(2):297-308. doi: 10.1038/s41430-021-00950-1. Epub 2021 Jun 11. Eur J Clin Nutr. 2022. PMID: 34117375 Free PMC article. Clinical Trial.

10

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.

Singh A, D'Amico D, Andreux PA, Fouassier AM, Blanco-Bose W, Evans M, Aebischer P, Auwerx J, Rinsch C. Singh A, et al. Cell Rep Med. 2022 May 17;3(5):100633. doi: 10.1016/j.xcrm.2022.100633. Cell Rep Med. 2022. PMID: 35584623 Free PMC article. Clinical Trial.

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