Brandt P - Search Results

1

Discovery of pyrazinone based compounds that potently inhibit the drug-resistant enzyme variant R155K of the hepatitis C virus NS3 protease.

Belfrage AK, Abdurakhmanov E, Kerblom E, Brandt P, Oshalim A, Gising J, Skogh A, Neyts J, Danielson UH, Sandström A. Belfrage AK, et al. Among authors: brandt p. Bioorg Med Chem. 2016 Jun 15;24(12):2603-20. doi: 10.1016/j.bmc.2016.03.066. Epub 2016 Apr 8. Bioorg Med Chem. 2016. PMID: 27160057

2

Pan-NS3 protease inhibitors of hepatitis C virus based on an R³-elongated pyrazinone scaffold.

Belfrage AK, Abdurakhmanov E, Åkerblom E, Brandt P, Alogheli H, Neyts J, Danielson UH, Sandström A. Belfrage AK, et al. Among authors: brandt p. Eur J Med Chem. 2018 Mar 25;148:453-464. doi: 10.1016/j.ejmech.2018.02.032. Epub 2018 Feb 13. Eur J Med Chem. 2018. PMID: 29477077

3

Identification of a novel scaffold for allosteric inhibition of wild type and drug resistant HIV-1 reverse transcriptase by fragment library screening.

Geitmann M, Elinder M, Seeger C, Brandt P, de Esch IJ, Danielson UH. Geitmann M, et al. Among authors: brandt p. J Med Chem. 2011 Feb 10;54(3):699-708. doi: 10.1021/jm1010513. Epub 2011 Jan 5. J Med Chem. 2011. PMID: 21207961

4

Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB).

De Rosa M, Lu L, Zamaratski E, Szałaj N, Cao S, Wadensten H, Lenhammar L, Gising J, Roos AK, Huseby DL, Larsson R, Andrén PE, Hughes D, Brandt P, Mowbray SL, Karlén A. De Rosa M, et al. Among authors: brandt p. Bioorg Med Chem. 2017 Feb 1;25(3):897-911. doi: 10.1016/j.bmc.2016.12.003. Epub 2016 Dec 7. Bioorg Med Chem. 2017. PMID: 28038943 Free article.

5

Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments.

Brandt P, Geitmann M, Danielson UH. Brandt P, et al. J Med Chem. 2011 Feb 10;54(3):709-18. doi: 10.1021/jm101052g. Epub 2011 Jan 5. J Med Chem. 2011. PMID: 21207958

6

Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties.

Borhade SR, Svensson R, Brandt P, Artursson P, Arvidsson PI, Sandström A. Borhade SR, et al. Among authors: brandt p. ChemMedChem. 2015 Mar;10(3):455-60. doi: 10.1002/cmdc.201402497. Epub 2015 Jan 28. ChemMedChem. 2015. PMID: 25630705

7

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.

Brem J, Panduwawala T, Hansen JU, Hewitt J, Liepins E, Donets P, Espina L, Farley AJM, Shubin K, Campillos GG, Kiuru P, Shishodia S, Krahn D, Leśniak RK, Schmidt Adrian J, Calvopiña K, Turrientes MC, Kavanagh ME, Lubriks D, Hinchliffe P, Langley GW, Aboklaish AF, Eneroth A, Backlund M, Baran AG, Nielsen EI, Speake M, Kuka J, Robinson J, Grinberga S, Robinson L, McDonough MA, Rydzik AM, Leissing TM, Jimenez-Castellanos JC, Avison MB, Da Silva Pinto S, Pannifer AD, Martjuga M, Widlake E, Priede M, Hopkins Navratilova I, Gniadkowski M, Belfrage AK, Brandt P, Yli-Kauhaluoma J, Bacque E, Page MGP, Björkling F, Tyrrell JM, Spencer J, Lang PA, Baranczewski P, Cantón R, McElroy SP, Jones PS, Baquero F, Suna E, Morrison A, Walsh TR, Schofield CJ. Brem J, et al. Among authors: brandt p. Nat Chem. 2022 Jan;14(1):15-24. doi: 10.1038/s41557-021-00831-x. Epub 2021 Dec 13. Nat Chem. 2022. PMID: 34903857

8

Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki-Heck Annulations.

Lindman J, Gopalan G, Palo-Nieto C, Brandt P, Gising J, Larhed M. Lindman J, et al. Among authors: brandt p. ACS Omega. 2022 Aug 26;7(36):32525-32535. doi: 10.1021/acsomega.2c04111. eCollection 2022 Sep 13. ACS Omega. 2022. PMID: 36120037 Free PMC article.

9

Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase.

Szałaj N, Lu L, Benediktsdottir A, Zamaratski E, Cao S, Olanders G, Hedgecock C, Karlén A, Erdélyi M, Hughes D, Mowbray SL, Brandt P. Szałaj N, et al. Among authors: brandt p. Eur J Med Chem. 2018 Sep 5;157:1346-1360. doi: 10.1016/j.ejmech.2018.08.086. Epub 2018 Aug 30. Eur J Med Chem. 2018. PMID: 30196059

10

Computational studies of molecular pre-organization through macrocyclization: Conformational distribution analysis of closely related non-macrocyclic and macrocyclic analogs.

Olanders G, Brandt P, Sköld C, Karlén A. Olanders G, et al. Among authors: brandt p. Bioorg Med Chem. 2021 Nov 1;49:116399. doi: 10.1016/j.bmc.2021.116399. Epub 2021 Sep 11. Bioorg Med Chem. 2021. PMID: 34601455 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,023 results

Search Page

Filters