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The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells.
Jeffries TL Jr, Sacha CR, Pollara J, Himes J, Jaeger FH, Dennison SM, McGuire E, Kunz E, Eudailey JA, Trama AM, LaBranche C, Fouda GG, Wiehe K, Montefiori DC, Haynes BF, Liao HX, Ferrari G, Alam SM, Moody MA, Permar SR. Jeffries TL Jr, et al. Among authors: mcguire e. Mucosal Immunol. 2016 Mar;9(2):414-27. doi: 10.1038/mi.2015.70. Epub 2015 Aug 5. Mucosal Immunol. 2016. PMID: 26242599 Free PMC article.
HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine.
McGuire EP, Fong Y, Toote C, Cunningham CK, McFarland EJ, Borkowsky W, Barnett S, Itell HL, Kumar A, Gray G, McElrath MJ, Tomaras GD, Permar SR, Fouda GG. McGuire EP, et al. J Virol. 2017 Dec 14;92(1):e01070-17. doi: 10.1128/JVI.01070-17. Print 2018 Jan 1. J Virol. 2017. PMID: 29021402 Free PMC article. Clinical Trial.
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
Pollara J, McGuire E, Fouda GG, Rountree W, Eudailey J, Overman RG, Seaton KE, Deal A, Edwards RW, Tegha G, Kamwendo D, Kumwenda J, Nelson JA, Liao HX, Brinkley C, Denny TN, Ochsenbauer C, Ellington S, King CC, Jamieson DJ, van der Horst C, Kourtis AP, Tomaras GD, Ferrari G, Permar SR. Pollara J, et al. Among authors: mcguire e. J Virol. 2015 Oct;89(19):9952-61. doi: 10.1128/JVI.01560-15. Epub 2015 Jul 22. J Virol. 2015. PMID: 26202232 Free PMC article. Clinical Trial.
Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk.
Martinez DR, Vandergrift N, Douglas AO, McGuire E, Bainbridge J, Nicely NI, Montefiori DC, Tomaras GD, Fouda GG, Permar SR. Martinez DR, et al. Among authors: mcguire e. J Virol. 2017 Apr 13;91(9):e02422-16. doi: 10.1128/JVI.02422-16. Print 2017 May 1. J Virol. 2017. PMID: 28202762 Free PMC article.
Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
Kumar A, Smith CEP, Giorgi EE, Eudailey J, Martinez DR, Yusim K, Douglas AO, Stamper L, McGuire E, LaBranche CC, Montefiori DC, Fouda GG, Gao F, Permar SR. Kumar A, et al. Among authors: mcguire e. PLoS Pathog. 2018 Apr 19;14(4):e1006944. doi: 10.1371/journal.ppat.1006944. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29672607 Free PMC article.
Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1.
Tay MZ, Kunz EL, Deal A, Zhang L, Seaton KE, Rountree W, Eudailey JA, Heptinstall J, McRaven MD, Matias E, McGuire E, Yates NL, Perez LG, Montefiori DC, Overman RG, Hope TJ, Shen X, Kalilani L, Fouda GG, Tomaras GD, Permar SR. Tay MZ, et al. Among authors: mcguire e. J Virol. 2019 Mar 21;93(7):e02084-18. doi: 10.1128/JVI.02084-18. Print 2019 Apr 1. J Virol. 2019. PMID: 30700599 Free PMC article.
Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women.
Sacha CR, Vandergrift N, Jeffries TL Jr, McGuire E, Fouda GG, Liebl B, Marshall DJ, Gurley TC, Stiegel L, Whitesides JF, Friedman J, Badiabo A, Foulger A, Yates NL, Tomaras GD, Kepler TB, Liao HX, Haynes BF, Moody MA, Permar SR. Sacha CR, et al. Among authors: mcguire e. Mucosal Immunol. 2015 Mar;8(2):316-26. doi: 10.1038/mi.2014.69. Epub 2014 Aug 6. Mucosal Immunol. 2015. PMID: 25100291 Free PMC article.
480 results