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Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.
Ferdaoussi M, Dai X, Jensen MV, Wang R, Peterson BS, Huang C, Ilkayeva O, Smith N, Miller N, Hajmrle C, Spigelman AF, Wright RC, Plummer G, Suzuki K, Mackay JP, van de Bunt M, Gloyn AL, Ryan TE, Norquay LD, Brosnan MJ, Trimmer JK, Rolph TP, Kibbey RG, Manning Fox JE, Colmers WF, Shirihai OS, Neufer PD, Yeh ET, Newgard CB, MacDonald PE. Ferdaoussi M, et al. J Clin Invest. 2015 Oct 1;125(10):3847-60. doi: 10.1172/JCI82498. Epub 2015 Sep 21. J Clin Invest. 2015. PMID: 26389676 Free PMC article.
Islet Brain 1 Protects Insulin Producing Cells against Lipotoxicity.
Brajkovic S, Ferdaoussi M, Pawlowski V, Ezanno H, Plaisance V, Zmuda E, Hai T, Annicotte JS, Waeber G, Abderrahmani A. Brajkovic S, et al. Among authors: ferdaoussi m. J Diabetes Res. 2016;2016:9158562. doi: 10.1155/2016/9158562. Epub 2015 Nov 9. J Diabetes Res. 2016. PMID: 26665154 Free PMC article.
Interleukin-1 signaling contributes to acute islet compensation.
Hajmrle C, Smith N, Spigelman AF, Dai X, Senior L, Bautista A, Ferdaoussi M, MacDonald PE. Hajmrle C, et al. Among authors: ferdaoussi m. JCI Insight. 2016 Apr 7;1(4):e86055. doi: 10.1172/jci.insight.86055. JCI Insight. 2016. PMID: 27699257 Free PMC article.
Toward Connecting Metabolism to the Exocytotic Site.
Ferdaoussi M, MacDonald PE. Ferdaoussi M, et al. Trends Cell Biol. 2017 Mar;27(3):163-171. doi: 10.1016/j.tcb.2016.10.003. Epub 2016 Dec 5. Trends Cell Biol. 2017. PMID: 27932063 Review.
42 results