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Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils.
Barthelmes J, de Bazo AM, Pewzner-Jung Y, Schmitz K, Mayer CA, Foerch C, Eberle M, Tafferner N, Ferreirós N, Henke M, Geisslinger G, Futerman AH, Grösch S, Schiffmann S. Barthelmes J, et al. Among authors: tafferner n. Brain Behav Immun. 2015 May;46:280-92. doi: 10.1016/j.bbi.2015.02.010. Epub 2015 Feb 16. Brain Behav Immun. 2015. PMID: 25697397
Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils.
Eberle M, Ebel P, Mayer CA, Barthelmes J, Tafferner N, Ferreiros N, Ulshöfer T, Henke M, Foerch C, de Bazo AM, Grösch S, Geisslinger G, Willecke K, Schiffmann S. Eberle M, et al. Among authors: tafferner n. Immunol Cell Biol. 2015 Oct;93(9):825-36. doi: 10.1038/icb.2015.47. Epub 2015 Apr 2. Immunol Cell Biol. 2015. PMID: 25833068