Merkel JS - Search Results

1

Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.

Gale M, Sayegh J, Cao J, Norcia M, Gareiss P, Hoyer D, Merkel JS, Yan Q. Gale M, et al. Among authors: merkel js. Oncotarget. 2016 Jun 28;7(26):39931-39944. doi: 10.18632/oncotarget.9539. Oncotarget. 2016. PMID: 27224921 Free PMC article.

2

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q. Sayegh J, et al. Among authors: merkel js. J Biol Chem. 2013 Mar 29;288(13):9408-17. doi: 10.1074/jbc.M112.419861. Epub 2013 Feb 13. J Biol Chem. 2013. PMID: 23408432 Free PMC article.

3

YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.

Stachelek GC, Peterson-Roth E, Liu Y, Fernandez RJ 3rd, Pike LR, Qian JM, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer PM. Stachelek GC, et al. Mol Cancer Res. 2015 Oct;13(10):1389-97. doi: 10.1158/1541-7786.MCR-15-0036. Epub 2015 Jun 26. Mol Cancer Res. 2015. PMID: 26116172 Free PMC article.

4

Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma.

Scholl UI, Abriola L, Zhang C, Reimer EN, Plummer M, Kazmierczak BI, Zhang J, Hoyer D, Merkel JS, Wang W, Lifton RP. Scholl UI, et al. Among authors: merkel js. J Clin Invest. 2017 Jun 30;127(7):2739-2750. doi: 10.1172/JCI91733. Epub 2017 Jun 12. J Clin Invest. 2017. PMID: 28604387 Free PMC article.

5

Drug repositioning and pharmacophore identification in the discovery of hookworm MIF inhibitors.

Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E. Cho Y, et al. Among authors: merkel js. Chem Biol. 2011 Sep 23;18(9):1089-101. doi: 10.1016/j.chembiol.2011.07.011. Chem Biol. 2011. PMID: 21944748 Free PMC article.

6

DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.

Nemec AA, Abriola L, Merkel JS, de Stanchina E, DeVeaux M, Zelterman D, Glazer PM, Sweasy JB. Nemec AA, et al. Among authors: merkel js. Mol Cancer Res. 2017 Mar;15(3):269-280. doi: 10.1158/1541-7786.MCR-16-0227-T. Epub 2017 Jan 10. Mol Cancer Res. 2017. PMID: 28074003 Free PMC article.

7

Determinants of mammalian nucleolar architecture.

Farley KI, Surovtseva Y, Merkel J, Baserga SJ. Farley KI, et al. Chromosoma. 2015 Sep;124(3):323-31. doi: 10.1007/s00412-015-0507-z. Epub 2015 Feb 12. Chromosoma. 2015. PMID: 25670395 Free PMC article. Review.

8

Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs.

Lewis CA, Merkel J, Miller SJ. Lewis CA, et al. Bioorg Med Chem Lett. 2008 Nov 15;18(22):6007-11. doi: 10.1016/j.bmcl.2008.09.019. Epub 2008 Sep 9. Bioorg Med Chem Lett. 2008. PMID: 18819795 Free PMC article.

9

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number.

Farley-Barnes KI, McCann KL, Ogawa LM, Merkel J, Surovtseva YV, Baserga SJ. Farley-Barnes KI, et al. Cell Rep. 2018 Feb 13;22(7):1923-1934. doi: 10.1016/j.celrep.2018.01.056. Cell Rep. 2018. PMID: 29444442 Free PMC article.

10

A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans.

Weicksel SE, Mahadav A, Moyle M, Cipriani PG, Kudron M, Pincus Z, Bahmanyar S, Abriola L, Merkel J, Gutwein M, Fernandez AG, Piano F, Gunsalus KC, Reinke V. Weicksel SE, et al. Development. 2016 Oct 1;143(19):3540-3548. doi: 10.1242/dev.140046. Epub 2016 Aug 10. Development. 2016. PMID: 27510972 Free PMC article.

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