Sayegh J - Search Results

1

Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.

Gale M, Sayegh J, Cao J, Norcia M, Gareiss P, Hoyer D, Merkel JS, Yan Q. Gale M, et al. Among authors: sayegh j. Oncotarget. 2016 Jun 28;7(26):39931-39944. doi: 10.18632/oncotarget.9539. Oncotarget. 2016. PMID: 27224921 Free PMC article.

2

Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.

Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q. Sayegh J, et al. J Biol Chem. 2013 Mar 29;288(13):9408-17. doi: 10.1074/jbc.M112.419861. Epub 2013 Feb 13. J Biol Chem. 2013. PMID: 23408432 Free PMC article.

3

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.

Blair LP, Cao J, Zou MR, Sayegh J, Yan Q. Blair LP, et al. Among authors: sayegh j. Cancers (Basel). 2011 Mar 1;3(1):1383-404. doi: 10.3390/cancers3011383. Cancers (Basel). 2011. PMID: 21544224 Free PMC article.

4

Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain.

Sayegh J, Webb K, Cheng D, Bedford MT, Clarke SG. Sayegh J, et al. J Biol Chem. 2007 Dec 14;282(50):36444-53. doi: 10.1074/jbc.M704650200. Epub 2007 Oct 9. J Biol Chem. 2007. PMID: 17925405 Free article.

5

A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei.

Fisk JC, Sayegh J, Zurita-Lopez C, Menon S, Presnyak V, Clarke SG, Read LK. Fisk JC, et al. Among authors: sayegh j. J Biol Chem. 2009 Apr 24;284(17):11590-600. doi: 10.1074/jbc.M807279200. Epub 2009 Mar 2. J Biol Chem. 2009. PMID: 19254949 Free PMC article.

6

PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family.

Lee J, Sayegh J, Daniel J, Clarke S, Bedford MT. Lee J, et al. Among authors: sayegh j. J Biol Chem. 2005 Sep 23;280(38):32890-6. doi: 10.1074/jbc.M506944200. Epub 2005 Jul 28. J Biol Chem. 2005. PMID: 16051612 Free article.

7

Hsl7 is a substrate-specific type II protein arginine methyltransferase in yeast.

Sayegh J, Clarke SG. Sayegh J, et al. Biochem Biophys Res Commun. 2008 Aug 8;372(4):811-5. doi: 10.1016/j.bbrc.2008.05.121. Epub 2008 Jun 2. Biochem Biophys Res Commun. 2008. PMID: 18515076 Free PMC article.

8

Evolutionarily divergent type II protein arginine methyltransferase in Trypanosoma brucei.

Pasternack DA, Sayegh J, Clarke S, Read LK. Pasternack DA, et al. Among authors: sayegh j. Eukaryot Cell. 2007 Sep;6(9):1665-81. doi: 10.1128/EC.00133-07. Epub 2007 Jun 29. Eukaryot Cell. 2007. PMID: 17601874 Free PMC article.

9

TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei.

Fisk JC, Zurita-Lopez C, Sayegh J, Tomasello DL, Clarke SG, Read LK. Fisk JC, et al. Among authors: sayegh j. Eukaryot Cell. 2010 Jun;9(6):866-77. doi: 10.1128/EC.00018-10. Epub 2010 Apr 23. Eukaryot Cell. 2010. PMID: 20418380 Free PMC article.

10

Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp.

Stetler A, Winograd C, Sayegh J, Cheever A, Patton E, Zhang X, Clarke S, Ceman S. Stetler A, et al. Among authors: sayegh j. Hum Mol Genet. 2006 Jan 1;15(1):87-96. doi: 10.1093/hmg/ddi429. Epub 2005 Nov 30. Hum Mol Genet. 2006. PMID: 16319129

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