Hansen T - Search Results

1

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stancáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, Wang S, Maruthur N, Michailidou K, Pirie A, van der Lee SJ, Gillson C, Al Olama AA, Amouyel P, Arriola L, Arveiler D, Aviles-Olmos I, Balkau B, Barricarte A, Barroso I, Garcia SB, Bis JC, Blankenberg S, Boehnke M, Boeing H, Boerwinkle E, Borecki IB, Bork-Jensen J, Bowden S, Caldas C, Caslake M; CVD50 consortium; Cupples LA, Cruchaga C, Czajkowski J, den Hoed M, Dunn JA, Earl HM, Ehret GB, Ferrannini E, Ferrieres J, Foltynie T, Ford I, Forouhi NG, Gianfagna F, Gonzalez C, Grioni S, Hiller L, Jansson JH, Jørgensen ME, Jukema JW, Kaaks R, Kee F, Kerrison ND, Key TJ, Kontto J, Kote-Jarai Z, Kraja AT, Kuulasmaa K, Kuusisto J, Linneberg A, Liu C, Marenne G, Mohlke KL, Morris AP, Muir K, Müller-Nurasyid M, Munroe PB, Navarro C, Nielsen SF, Nilsson PM, Nordestgaard BG, Packard CJ, Palli D, Panico S, Peloso GM, Perola M, Peters A, Poole CJ, Quirós JR, Rolandsson O, Sacerdote C, Salomaa V, Sánchez MJ, Sattar N, Sharp SJ, Sims R, Slimani N, Smith JA, Thompson DJ, Trompet S, Tumino R, van der A DL, van der Schouw YT, Virtamo J, Walker M, Walt… See abstract for full author list ➔ Scott RA, et al. Among authors: hansen t. Sci Transl Med. 2016 Jun 1;8(341):341ra76. doi: 10.1126/scitranslmed.aad3744. Sci Transl Med. 2016. PMID: 27252175 Free PMC article.

2

A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.

Echwald SM, Bach H, Vestergaard H, Richelsen B, Kristensen K, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O. Echwald SM, et al. Among authors: hansen t. Diabetes. 2002 Jan;51(1):1-6. doi: 10.2337/diabetes.51.1.1. Diabetes. 2002. PMID: 11756316

3

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha.

Almind K, Delahaye L, Hansen T, Van Obberghen E, Pedersen O, Kahn CR. Almind K, et al. Among authors: hansen t. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2124-8. doi: 10.1073/pnas.042688799. Epub 2002 Feb 12. Proc Natl Acad Sci U S A. 2002. PMID: 11842213 Free PMC article.

4

[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics].

Hansen T, Urhammer SA, Pedersen OB. Hansen T, et al. Ugeskr Laeger. 2002 Apr 8;164(15):2017-22. Ugeskr Laeger. 2002. PMID: 11984998 Review. Danish.

5

[Chasing the genetic determinants of the presumed polygenic forms of type 2 diabetes. Status and perspectives].

Pedersen OB, Hansen T, Hansen L, Echwald SM, Urhammer SA. Pedersen OB, et al. Among authors: hansen t, hansen l. Ugeskr Laeger. 2002 Apr 15;164(16):2163-6. Ugeskr Laeger. 2002. PMID: 11989062 Danish. No abstract available.

6

Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?

Poulsen P, Andersen G, Fenger M, Hansen T, Echwald SM, Vølund A, Beck-Nielsen H, Pedersen O, Vaag A. Poulsen P, et al. Among authors: hansen t. Diabetes. 2003 Jan;52(1):194-8. doi: 10.2337/diabetes.52.1.194. Diabetes. 2003. PMID: 12502512

7

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.

Nielsen EM, Hansen L, Carstensen B, Echwald SM, Drivsholm T, Glümer C, Thorsteinsson B, Borch-Johnsen K, Hansen T, Pedersen O. Nielsen EM, et al. Among authors: hansen t, hansen l. Diabetes. 2003 Feb;52(2):573-7. doi: 10.2337/diabetes.52.2.573. Diabetes. 2003. PMID: 12540638

8

Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects.

Nielsen EM, Hansen L, Echwald SM, Drivsholm T, Borch-Johnsen K, Ekstrøm CT, Hansen T, Pedersen O. Nielsen EM, et al. Among authors: hansen t, hansen l. Pharmacogenetics. 2003 Jul;13(7):417-23. doi: 10.1097/01.fpc.0000054105.48725.5c. Pharmacogenetics. 2003. PMID: 12835617

9

Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.

Andersen G, Rose CS, Hamid YH, Drivsholm T, Borch-Johnsen K, Hansen T, Pedersen O. Andersen G, et al. Among authors: hansen t. Diabetes. 2003 Sep;52(9):2445-8. doi: 10.2337/diabetes.52.9.2445. Diabetes. 2003. PMID: 12941788

10

Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population.

Lauenborg J, Hansen T, Jensen DM, Vestergaard H, Mølsted-Pedersen L, Hornnes P, Locht H, Pedersen O, Damm P. Lauenborg J, et al. Among authors: hansen t. Diabetes Care. 2004 May;27(5):1194-9. doi: 10.2337/diacare.27.5.1194. Diabetes Care. 2004. PMID: 15111544

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