Dokter WH - Search Results

1

Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance.

Toonen EJ, Mirea AM, Tack CJ, Stienstra R, Ballak DB, van Diepen JA, Hijmans A, Chavakis T, Dokter WH, Pham CT, Netea MG, Dinarello CA, Joosten LA. Toonen EJ, et al. Among authors: dokter wh. Mol Med. 2016 May 24;22:202-14. doi: 10.2119/molmed.2016.00033. Mol Med. 2016. PMID: 27261776 Free PMC article.

2

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.

Frijters R, Fleuren W, Toonen EJ, Tuckermann JP, Reichardt HM, van der Maaden H, van Elsas A, van Lierop MJ, Dokter W, de Vlieg J, Alkema W. Frijters R, et al. BMC Genomics. 2010 Jun 5;11:359. doi: 10.1186/1471-2164-11-359. BMC Genomics. 2010. PMID: 20525385 Free PMC article.

3

Prednisolone-induced changes in gene-expression profiles in healthy volunteers.

Toonen EJ, Fleuren WW, Nässander U, van Lierop MJ, Bauerschmidt S, Dokter WH, Alkema W. Toonen EJ, et al. Among authors: dokter wh. Pharmacogenomics. 2011 Jul;12(7):985-98. doi: 10.2217/pgs.11.34. Epub 2011 Jun 2. Pharmacogenomics. 2011. PMID: 21635145 Clinical Trial.

4

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells.

Linssen MM, van Raalte DH, Toonen EJ, Alkema W, van der Zon GC, Dokter WH, Diamant M, Guigas B, Ouwens DM. Linssen MM, et al. Among authors: dokter wh. Cell Signal. 2011 Nov;23(11):1708-15. doi: 10.1016/j.cellsig.2011.06.002. Epub 2011 Jun 13. Cell Signal. 2011. PMID: 21689745

5

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W. Fleuren WW, et al. Among authors: dokter wh. Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19. Arch Physiol Biochem. 2013. PMID: 23506355 Free PMC article.

6

Identification of gene signatures for prednisolone-induced metabolic dysfunction in collagen-induced arthritic mice.

Ellero-Simatos S, Fleuren WW, Bauerschmidt S, Dokter WH, Toonen EJ. Ellero-Simatos S, et al. Among authors: dokter wh. Pharmacogenomics. 2014 Apr;15(5):629-41. doi: 10.2217/pgs.14.3. Pharmacogenomics. 2014. PMID: 24798720

7

Glucose kinetics in the collagen-induced arthritis model: an all-in-one model to assess both efficacy and metabolic side effects of glucocorticoids.

Toonen EJ, Laskewitz AJ, van Dijk TH, Bleeker A, Grefhorst A, Schouten AE, Bastiaanssen EA, Ballak DB, Koenders MI, van Doorn C, van der Vleuten MA, van Lierop MJ, Groen AK, Dokter WH. Toonen EJ, et al. Among authors: dokter wh. PLoS One. 2014 Sep 2;9(9):e98684. doi: 10.1371/journal.pone.0098684. eCollection 2014. PLoS One. 2014. PMID: 25181348 Free PMC article.

8

Chronic prednisolone treatment aggravates hyperglycemia in mice fed a high-fat diet but does not worsen dietary fat-induced insulin resistance.

Laskewitz AJ, van Dijk TH, Grefhorst A, van Lierop MJ, Schreurs M, Bloks VW, Reijngoud DJ, Dokter WH, Kuipers F, Groen AK. Laskewitz AJ, et al. Among authors: dokter wh. Endocrinology. 2012 Aug;153(8):3713-23. doi: 10.1210/en.2011-1891. Epub 2012 May 31. Endocrinology. 2012. PMID: 22653558 Free article.

9

Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men.

van Raalte DH, Nofrate V, Bunck MC, van Iersel T, Elassaiss Schaap J, Nässander UK, Heine RJ, Mari A, Dokter WH, Diamant M. van Raalte DH, et al. Among authors: dokter wh. Eur J Endocrinol. 2010 Apr;162(4):729-35. doi: 10.1530/EJE-09-1034. Epub 2010 Feb 2. Eur J Endocrinol. 2010. PMID: 20124412 Clinical Trial.

10

Chronic prednisolone treatment reduces hepatic insulin sensitivity while perturbing the fed-to-fasting transition in mice.

Laskewitz AJ, van Dijk TH, Bloks VW, Reijngoud DJ, van Lierop MJ, Dokter WH, Kuipers F, Groen AK, Grefhorst A. Laskewitz AJ, et al. Among authors: dokter wh. Endocrinology. 2010 May;151(5):2171-8. doi: 10.1210/en.2009-1374. Epub 2010 Feb 25. Endocrinology. 2010. PMID: 20185761

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