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Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis.
Plater-Zyberk C, Joosten LA, Helsen MM, Sattonnet-Roche P, Siegfried C, Alouani S, van De Loo FA, Graber P, Aloni S, Cirillo R, Lubberts E, Dinarello CA, van Den Berg WB, Chvatchko Y. Plater-Zyberk C, et al. Among authors: joosten la. J Clin Invest. 2001 Dec;108(12):1825-32. doi: 10.1172/JCI12097. J Clin Invest. 2001. PMID: 11748266 Free PMC article.
The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome.
Radstake TR, Franke B, Hanssen S, Netea MG, Welsing P, Barrera P, Joosten LA, van Riel PL, van den Berg WB. Radstake TR, et al. Among authors: joosten la. Arthritis Rheum. 2004 Mar;50(3):999-1001. doi: 10.1002/art.20114. Arthritis Rheum. 2004. PMID: 15022344 Free article. No abstract available.
Toll-like receptor 2 controls expansion and function of regulatory T cells.
Sutmuller RP, den Brok MH, Kramer M, Bennink EJ, Toonen LW, Kullberg BJ, Joosten LA, Akira S, Netea MG, Adema GJ. Sutmuller RP, et al. Among authors: joosten la. J Clin Invest. 2006 Feb;116(2):485-94. doi: 10.1172/JCI25439. Epub 2006 Jan 19. J Clin Invest. 2006. PMID: 16424940 Free PMC article.
IL-32, a proinflammatory cytokine in rheumatoid arthritis.
Joosten LA, Netea MG, Kim SH, Yoon DY, Oppers-Walgreen B, Radstake TR, Barrera P, van de Loo FA, Dinarello CA, van den Berg WB. Joosten LA, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3298-303. doi: 10.1073/pnas.0511233103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492735 Free PMC article.
796 results