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Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion.
Capellera-Garcia S, Pulecio J, Dhulipala K, Siva K, Rayon-Estrada V, Singbrant S, Sommarin MN, Walkley CR, Soneji S, Karlsson G, Raya Á, Sankaran VG, Flygare J. Capellera-Garcia S, et al. Among authors: siva k. Cell Rep. 2016 Jun 14;15(11):2550-62. doi: 10.1016/j.celrep.2016.05.027. Epub 2016 Jun 2. Cell Rep. 2016. PMID: 27264182 Free PMC article.
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia.
Taylor AM, Macari ER, Chan IT, Blair MC, Doulatov S, Vo LT, Raiser DM, Siva K, Basak A, Pirouz M, Shah AN, McGrath K, Humphries JM, Stillman E, Alter BP, Calo E, Gregory RI, Sankaran VG, Flygare J, Ebert BL, Zhou Y, Daley GQ, Zon LI. Taylor AM, et al. Among authors: siva k. Sci Transl Med. 2020 Oct 21;12(566):eabb5831. doi: 10.1126/scitranslmed.abb5831. Sci Transl Med. 2020. PMID: 33087503 Free PMC article.
Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.
Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez CA, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Wilkes MC, et al. Among authors: siva k. Exp Hematol. 2020 Nov;91:65-77. doi: 10.1016/j.exphem.2020.09.187. Epub 2020 Sep 12. Exp Hematol. 2020. PMID: 32926965 Free PMC article.
Targeting elevated heme levels to treat a mouse model for Diamond-Blackfan Anemia.
Sjögren SE, Chen J, Mattebo A, Alattar AG, Karlsson H, Siva K, Soneji S, Tedgård U, Chen JJ, Gram M, Flygare J. Sjögren SE, et al. Among authors: siva k. Exp Hematol. 2022 Jan;105:50-61. doi: 10.1016/j.exphem.2021.10.005. Epub 2021 Oct 30. Exp Hematol. 2022. PMID: 34757171 Free PMC article.
Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells.
Warsi S, Dahl M, Smith EMK, Rydstrom A, Mansell E, Sigurdsson V, Sjoberg J, Soneji S, Rorby E, Siva K, Grahn THM, Liu Y, Blank U, Karlsson G, Karlsson S. Warsi S, et al. Among authors: siva k. Haematologica. 2022 Dec 1;107(12):2884-2896. doi: 10.3324/haematol.2021.279799. Haematologica. 2022. PMID: 35615926 Free PMC article.
40 results