Chen X - Search Results

1

Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells.

Cao D, Song X, Che L, Li X, Pilo MG, Vidili G, Porcu A, Solinas A, Cigliano A, Pes GM, Ribback S, Dombrowski F, Chen X, Li L, Calvisi DF. Cao D, et al. Among authors: chen x. Liver Int. 2017 Jan;37(1):80-89. doi: 10.1111/liv.13183. Epub 2016 Jul 6. Liver Int. 2017. PMID: 27264722 Free PMC article.

2

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver.

Li X, Tao J, Cigliano A, Sini M, Calderaro J, Azoulay D, Wang C, Liu Y, Jiang L, Evert K, Demartis MI, Ribback S, Utpatel K, Dombrowski F, Evert M, Calvisi DF, Chen X. Li X, et al. Among authors: chen x. Oncotarget. 2015 Apr 30;6(12):10102-15. doi: 10.18632/oncotarget.3546. Oncotarget. 2015. PMID: 25826091 Free PMC article.

3

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.

Li L, Pilo GM, Li X, Cigliano A, Latte G, Che L, Joseph C, Mela M, Wang C, Jiang L, Ribback S, Simile MM, Pascale RM, Dombrowski F, Evert M, Semenkovich CF, Chen X, Calvisi DF. Li L, et al. Among authors: chen x. J Hepatol. 2016 Feb;64(2):333-341. doi: 10.1016/j.jhep.2015.10.004. Epub 2015 Oct 22. J Hepatol. 2016. PMID: 26476289 Free PMC article.

4

Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.

Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, Demartis MI, Tao J, Gui B, Pilo MG, Ribback S, Dombrowski F, Evert M, Calvisi DF, Chen X. Wang C, et al. Among authors: chen x. Liver Int. 2016 Aug;36(8):1176-86. doi: 10.1111/liv.13055. Epub 2016 Jan 30. Liver Int. 2016. PMID: 26716908 Free PMC article.

5

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.

Hu J, Che L, Li L, Pilo MG, Cigliano A, Ribback S, Li X, Latte G, Mela M, Evert M, Dombrowski F, Zheng G, Chen X, Calvisi DF. Hu J, et al. Among authors: chen x. Sci Rep. 2016 Feb 9;6:20484. doi: 10.1038/srep20484. Sci Rep. 2016. PMID: 26857837 Free PMC article.

6

Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.

Li L, Che L, Tharp KM, Park HM, Pilo MG, Cao D, Cigliano A, Latte G, Xu Z, Ribback S, Dombrowski F, Evert M, Gores GJ, Stahl A, Calvisi DF, Chen X. Li L, et al. Among authors: chen x. Hepatology. 2016 Jun;63(6):1900-13. doi: 10.1002/hep.28508. Epub 2016 Mar 25. Hepatology. 2016. PMID: 26910791 Free PMC article.

7

Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.

Che L, Pilo MG, Cigliano A, Latte G, Simile MM, Ribback S, Dombrowski F, Evert M, Chen X, Calvisi DF. Che L, et al. Among authors: chen x. Cell Cycle. 2017 Mar 19;16(6):499-507. doi: 10.1080/15384101.2017.1282586. Epub 2017 Jan 24. Cell Cycle. 2017. PMID: 28118080 Free PMC article.

8

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

Liu P, Ge M, Hu J, Li X, Che L, Sun K, Cheng L, Huang Y, Pilo MG, Cigliano A, Pes GM, Pascale RM, Brozzetti S, Vidili G, Porcu A, Cossu A, Palmieri G, Sini MC, Ribback S, Dombrowski F, Tao J, Calvisi DF, Chen L, Chen X. Liu P, et al. Among authors: chen l, chen x. Hepatology. 2017 Jul;66(1):167-181. doi: 10.1002/hep.29183. Epub 2017 May 22. Hepatology. 2017. PMID: 28370287 Free PMC article.

9

Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis.

Lee SA, Ladu S, Evert M, Dombrowski F, De Murtas V, Chen X, Calvisi DF. Lee SA, et al. Among authors: chen x. Hepatology. 2010 Aug;52(2):506-17. doi: 10.1002/hep.23681. Hepatology. 2010. PMID: 20683950 Free PMC article.

10

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J, Brozzetti S, Staniscia T, Chen X, Dombrowski F, Evert M. Calvisi DF, et al. Among authors: chen x. Gastroenterology. 2011 Mar;140(3):1071-83. doi: 10.1053/j.gastro.2010.12.006. Epub 2010 Dec 11. Gastroenterology. 2011. PMID: 21147110 Free PMC article.

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