Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.
Pingoud-Meier C, Lang D, Janss AJ, Rorke LB, Phillips PC, Shalaby T, Grotzer MA.
Pingoud-Meier C, et al.
Clin Cancer Res. 2003 Dec 15;9(17):6401-9.
Clin Cancer Res. 2003.
PMID: 14695141
In medulloblastoma (MB) cell lines, resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis was recently shown to correlate with loss of caspase-8 mRNA expression, because of aberrant gene methylation (M. A. Grotzer et al., Oncogene, …
In medulloblastoma (MB) cell lines, resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis was recently sho …