Ferber G - Search Results

1

Can Bias Evaluation Provide Protection Against False-Negative Results in QT Studies Without a Positive Control Using Exposure-Response Analysis?

Ferber G, Zhou M, Dota C, Garnett C, Keirns J, Malik M, Stockbridge N, Darpo B. Ferber G, et al. J Clin Pharmacol. 2017 Jan;57(1):85-95. doi: 10.1002/jcph.779. Epub 2016 Jul 7. J Clin Pharmacol. 2017. PMID: 27271102

2

Characterization of the human QT interval: novel distribution-based assessment of the repolarization effects of moxifloxacin.

Holzgrefe HH, Ferber G, Morrison R, Meyer O, Greiter-Wilke A, Singer T. Holzgrefe HH, et al. Among authors: ferber g. J Clin Pharmacol. 2012 Aug;52(8):1222-39. doi: 10.1177/0091270011409234. Epub 2011 Jun 9. J Clin Pharmacol. 2012. PMID: 21659628

3

Shortening of the QT interval after food can be used to demonstrate assay sensitivity in thorough QT studies.

Taubel J, Wong AH, Naseem A, Ferber G, Camm AJ. Taubel J, et al. Among authors: ferber g. J Clin Pharmacol. 2012 Oct;52(10):1558-65. doi: 10.1177/0091270011419851. Epub 2011 Nov 8. J Clin Pharmacol. 2012. PMID: 22067197 Clinical Trial.

4

Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects (pages.

Sugiyama A, Nakamura Y, Nishimura S, Adachi-Akahane S, Kumagai Y, Gayed J, Naseem A, Ferber G, Taubel J, Camm J. Sugiyama A, et al. Among authors: ferber g. Br J Clin Pharmacol. 2012 Mar;73(3):455-9. doi: 10.1111/j.1365-2125.2011.04110.x. Br J Clin Pharmacol. 2012. PMID: 22442827 Free PMC article.

5

Insulin at normal physiological levels does not prolong QT(c) interval in thorough QT studies performed in healthy volunteers.

Taubel J, Lorch U, Ferber G, Singh J, Batchvarov VN, Savelieva I, Camm AJ. Taubel J, et al. Among authors: ferber g. Br J Clin Pharmacol. 2013 Feb;75(2):392-403. doi: 10.1111/j.1365-2125.2012.04376.x. Br J Clin Pharmacol. 2013. PMID: 22775199 Free PMC article. Clinical Trial.

6

Assessment of the cardiac safety and pharmacokinetics of a short course, twice daily dose of orally-administered mifepristone in healthy male subjects.

Darpo B, Bullingham R, Combs DL, Ferber G, Hafez K. Darpo B, et al. Among authors: ferber g. Cardiol J. 2013;20(2):152-60. doi: 10.5603/CJ.2013.0028. Cardiol J. 2013. PMID: 23558873 Free article. Clinical Trial.

7

Thorough QT study of the effect of oral moxifloxacin on QTc interval in the fed and fasted state in healthy Japanese and Caucasian subjects.

Taubel J, Ferber G, Lorch U, Batchvarov V, Savelieva I, Camm AJ. Taubel J, et al. Among authors: ferber g. Br J Clin Pharmacol. 2014 Jan;77(1):170-9. doi: 10.1111/bcp.12168. Br J Clin Pharmacol. 2014. PMID: 23713767 Free PMC article. Clinical Trial.

8

Lomitapide at supratherapeutic plasma levels does not prolong the Qtc interval--results from a TQT study with moxifloxacin and ketoconazole.

Darpo B, Ferber G, Zhou M, Sumeray M, Sager P. Darpo B, et al. Among authors: ferber g. Ann Noninvasive Electrocardiol. 2013 Nov;18(6):577-89. doi: 10.1111/anec.12103. Epub 2013 Sep 30. Ann Noninvasive Electrocardiol. 2013. PMID: 24118671 Free PMC article. Clinical Trial.

9

The IQ-CSRC prospective clinical Phase 1 study: "Can early QT assessment using exposure response analysis replace the thorough QT study?".

Darpo B, Sarapa N, Garnett C, Benson C, Dota C, Ferber G, Jarugula V, Johannesen L, Keirns J, Krudys K, Ortemann-Renon C, Riley S, Rogers-Subramaniam D, Stockbridge N. Darpo B, et al. Among authors: ferber g. Ann Noninvasive Electrocardiol. 2014 Jan;19(1):70-81. doi: 10.1111/anec.12128. Epub 2013 Dec 30. Ann Noninvasive Electrocardiol. 2014. PMID: 24372708 Free PMC article. Review.

10

Importance of subject-specific QT/RR curvatures in the design of individual heart rate corrections of the QT interval.

Ferber G, Zhou M M, Darpo B. Ferber G, et al. J Electrocardiol. 2014 May-Jun;47(3):385-6. doi: 10.1016/j.jelectrocard.2013.12.010. Epub 2013 Dec 28. J Electrocardiol. 2014. PMID: 24468293 No abstract available.

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