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Interaction of Tarantula Venom Peptide ProTx-II with Lipid Membranes Is a Prerequisite for Its Inhibition of Human Voltage-gated Sodium Channel NaV1.7.
Henriques ST, Deplazes E, Lawrence N, Cheneval O, Chaousis S, Inserra M, Thongyoo P, King GF, Mark AE, Vetter I, Craik DJ, Schroeder CI. Henriques ST, et al. Among authors: lawrence n. J Biol Chem. 2016 Aug 12;291(33):17049-65. doi: 10.1074/jbc.M116.729095. Epub 2016 Jun 16. J Biol Chem. 2016. PMID: 27311819 Free PMC article.
Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7.
Agwa AJ, Lawrence N, Deplazes E, Cheneval O, Chen RM, Craik DJ, Schroeder CI, Henriques ST. Agwa AJ, et al. Among authors: lawrence n. Biochim Biophys Acta Biomembr. 2017 May;1859(5):835-844. doi: 10.1016/j.bbamem.2017.01.020. Epub 2017 Jan 20. Biochim Biophys Acta Biomembr. 2017. PMID: 28115115 Free article.
Redesigned Spider Peptide with Improved Antimicrobial and Anticancer Properties.
Troeira Henriques S, Lawrence N, Chaousis S, Ravipati AS, Cheneval O, Benfield AH, Elliott AG, Kavanagh AM, Cooper MA, Chan LY, Huang YH, Craik DJ. Troeira Henriques S, et al. Among authors: lawrence n. ACS Chem Biol. 2017 Sep 15;12(9):2324-2334. doi: 10.1021/acschembio.7b00459. Epub 2017 Aug 8. ACS Chem Biol. 2017. PMID: 28741926
Corrigendum to "Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7" [Biochim. Biophys. Acta 1859(5) (2017) 835-844].
Agwa AJ, Lawrence N, Deplazes E, Cheneval O, Chen RM, Craik DJ, Schroeder CI, Henriques ST. Agwa AJ, et al. Among authors: lawrence n. Biochim Biophys Acta Biomembr. 2017 Nov;1859(11):2277. doi: 10.1016/j.bbamem.2017.08.008. Epub 2017 Aug 25. Biochim Biophys Acta Biomembr. 2017. PMID: 28842331 Free article. No abstract available.
Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix-Loop-Helix Peptides with Cell Penetrating and Tumor Suppressor Properties.
Philippe GJ, Gaspar D, Sheng C, Huang YH, Benfield AH, Condon ND, Weidmann J, Lawrence N, Löwer A, Castanho MARB, Craik DJ, Troeira Henriques S. Philippe GJ, et al. Among authors: lawrence n. ACS Chem Biol. 2019 Sep 20;14(9):2071-2087. doi: 10.1021/acschembio.9b00593. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31390185
681 results