Law RP - Search Results

1

GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain.

Bamborough P, Barnett HA, Becher I, Bird MJ, Chung CW, Craggs PD, Demont EH, Diallo H, Fallon DJ, Gordon LJ, Grandi P, Hobbs CI, Hooper-Greenhill E, Jones EJ, Law RP, Le Gall A, Lugo D, Michon AM, Mitchell DJ, Prinjha RK, Sheppard RJ, Watson AJ, Watson RJ. Bamborough P, et al. Among authors: law rp. ACS Med Chem Lett. 2016 May 9;7(6):552-7. doi: 10.1021/acsmedchemlett.6b00092. eCollection 2016 Jun 9. ACS Med Chem Lett. 2016. PMID: 27326325 Free PMC article.

2

A modular synthesis of functionalised phenols enabled by controlled boron speciation.

Molloy JJ, Law RP, Fyfe JW, Seath CP, Hirst DJ, Watson AJ. Molloy JJ, et al. Among authors: law rp. Org Biomol Chem. 2015 Mar 14;13(10):3093-102. doi: 10.1039/c5ob00078e. Org Biomol Chem. 2015. PMID: 25628154 Free article.

3

Chan-Evans-Lam Amination of Boronic Acid Pinacol (BPin) Esters: Overcoming the Aryl Amine Problem.

Vantourout JC, Law RP, Isidro-Llobet A, Atkinson SJ, Watson AJ. Vantourout JC, et al. Among authors: law rp. J Org Chem. 2016 May 6;81(9):3942-50. doi: 10.1021/acs.joc.6b00466. Epub 2016 Apr 18. J Org Chem. 2016. PMID: 27045570 Free article.

4

Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.

Law RP, Atkinson SJ, Bamborough P, Chung CW, Demont EH, Gordon LJ, Lindon M, Prinjha RK, Watson AJB, Hirst DJ. Law RP, et al. J Med Chem. 2018 May 24;61(10):4317-4334. doi: 10.1021/acs.jmedchem.7b01666. Epub 2018 May 3. J Med Chem. 2018. PMID: 29656650

5

Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACs.

Stevens R, Bendito-Moll E, Battersby DJ, Miah AH, Wellaway N, Law RP, Stacey P, Klimaszewska D, Macina JM, Burley GA, Harling JD. Stevens R, et al. Among authors: law rp. J Med Chem. 2023 Nov 23;66(22):15437-15452. doi: 10.1021/acs.jmedchem.3c01604. Epub 2023 Nov 7. J Med Chem. 2023. PMID: 37933562

6

Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.

Law RP, Nunes J, Chung CW, Bantscheff M, Buda K, Dai H, Evans JP, Flinders A, Klimaszewska D, Lewis AJ, Muelbaier M, Scott-Stevens P, Stacey P, Tame CJ, Watt GF, Zinn N, Queisser MA, Harling JD, Benowitz AB. Law RP, et al. Angew Chem Int Ed Engl. 2021 Oct 18;60(43):23327-23334. doi: 10.1002/anie.202109237. Epub 2021 Sep 17. Angew Chem Int Ed Engl. 2021. PMID: 34416073

7

A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications.

Stacey P, Lithgow H, Lewell X, Konopacka A, Besley S, Green G, Whatling R, Law R, Röth S, Sapkota GP, Smith IED, Burley GA, Harling J, Benowitz AB, Queisser MA, Muelbaier M. Stacey P, et al. SLAS Discov. 2021 Aug;26(7):885-895. doi: 10.1177/24725552211017517. Epub 2021 May 27. SLAS Discov. 2021. PMID: 34041938 Free article.

8

Patterns of Suicide Ideation Across Eight Countries in Four Continents During the COVID-19 Pandemic Era: Repeated Cross-sectional Study.

Schluter PJ, Généreux M, Hung KK, Landaverde E, Law RP, Mok CPY, Murray V, O'Sullivan T, Qadar Z, Roy M. Schluter PJ, et al. Among authors: law rp. JMIR Public Health Surveill. 2022 Jan 17;8(1):e32140. doi: 10.2196/32140. JMIR Public Health Surveill. 2022. PMID: 34727524 Free PMC article.

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