Outeiro TF - Search Results

1

C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.

Kleinknecht A, Popova B, Lázaro DF, Pinho R, Valerius O, Outeiro TF, Braus GH. Kleinknecht A, et al. Among authors: outeiro tf. PLoS Genet. 2016 Jun 24;12(6):e1006098. doi: 10.1371/journal.pgen.1006098. eCollection 2016 Jun. PLoS Genet. 2016. PMID: 27341336 Free PMC article.

2

Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.

Büttner S, Delay C, Franssens V, Bammens T, Ruli D, Zaunschirm S, de Oliveira RM, Outeiro TF, Madeo F, Buée L, Galas MC, Winderickx J. Büttner S, et al. Among authors: outeiro tf. PLoS One. 2010 Oct 27;5(10):e13700. doi: 10.1371/journal.pone.0013700. PLoS One. 2010. PMID: 21060871 Free PMC article.

3

Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome.

Petroi D, Popova B, Taheri-Talesh N, Irniger S, Shahpasandzadeh H, Zweckstetter M, Outeiro TF, Braus GH. Petroi D, et al. Among authors: outeiro tf. J Biol Chem. 2012 Aug 10;287(33):27567-79. doi: 10.1074/jbc.M112.361865. Epub 2012 Jun 21. J Biol Chem. 2012. PMID: 22722939 Free PMC article.

4

Alpha-synuclein and intracellular trafficking: impact on the spreading of Parkinson's disease pathology.

Eisbach SE, Outeiro TF. Eisbach SE, et al. Among authors: outeiro tf. J Mol Med (Berl). 2013 Jun;91(6):693-703. doi: 10.1007/s00109-013-1038-9. Epub 2013 Apr 25. J Mol Med (Berl). 2013. PMID: 23616088 Review.

5

PLK2 modulates α-synuclein aggregation in yeast and mammalian cells.

Basso E, Antas P, Marijanovic Z, Gonçalves S, Tenreiro S, Outeiro TF. Basso E, et al. Among authors: outeiro tf. Mol Neurobiol. 2013 Dec;48(3):854-62. doi: 10.1007/s12035-013-8473-z. Epub 2013 May 17. Mol Neurobiol. 2013. PMID: 23677647

6

Limelight on alpha-synuclein: pathological and mechanistic implications in neurodegeneration.

Wales P, Pinho R, Lázaro DF, Outeiro TF. Wales P, et al. Among authors: outeiro tf. J Parkinsons Dis. 2013;3(4):415-59. doi: 10.3233/JPD-130216. J Parkinsons Dis. 2013. PMID: 24270242 Review.

7

Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease.

Tenreiro S, Reimão-Pinto MM, Antas P, Rino J, Wawrzycka D, Macedo D, Rosado-Ramos R, Amen T, Waiss M, Magalhães F, Gomes A, Santos CN, Kaganovich D, Outeiro TF. Tenreiro S, et al. Among authors: outeiro tf. PLoS Genet. 2014 May 8;10(5):e1004302. doi: 10.1371/journal.pgen.1004302. eCollection 2014 May. PLoS Genet. 2014. PMID: 24810576 Free PMC article.

8

α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.

Yin G, Lopes da Fonseca T, Eisbach SE, Anduaga AM, Breda C, Orcellet ML, Szegő ÉM, Guerreiro P, Lázaro DF, Braus GH, Fernandez CO, Griesinger C, Becker S, Goody RS, Itzen A, Giorgini F, Outeiro TF, Zweckstetter M. Yin G, et al. Among authors: outeiro tf. Neurobiol Dis. 2014 Oct;70:149-61. doi: 10.1016/j.nbd.2014.06.018. Epub 2014 Jun 28. Neurobiol Dis. 2014. PMID: 24983211

9

Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells.

Perfeito R, Lázaro DF, Outeiro TF, Rego AC. Perfeito R, et al. Among authors: outeiro tf. Mol Cell Neurosci. 2014 Sep;62:51-9. doi: 10.1016/j.mcn.2014.08.002. Epub 2014 Aug 7. Mol Cell Neurosci. 2014. PMID: 25109238

10

Interplay between sumoylation and phosphorylation for protection against α-synuclein inclusions.

Shahpasandzadeh H, Popova B, Kleinknecht A, Fraser PE, Outeiro TF, Braus GH. Shahpasandzadeh H, et al. Among authors: outeiro tf. J Biol Chem. 2014 Nov 7;289(45):31224-40. doi: 10.1074/jbc.M114.559237. Epub 2014 Sep 17. J Biol Chem. 2014. PMID: 25231978 Free PMC article.

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