Winkler TH - Search Results

1

Siglec-H protects from virus-triggered severe systemic autoimmunity.

Schmitt H, Sell S, Koch J, Seefried M, Sonnewald S, Daniel C, Winkler TH, Nitschke L. Schmitt H, et al. Among authors: winkler th. J Exp Med. 2016 Jul 25;213(8):1627-44. doi: 10.1084/jem.20160189. Epub 2016 Jul 4. J Exp Med. 2016. PMID: 27377589 Free PMC article.

2

Role of apoptosis in autoimmunity.

Lorenz HM, Herrmann M, Winkler T, Gaipl U, Kalden JR. Lorenz HM, et al. Apoptosis. 2000 Nov;5(5):443-9. doi: 10.1023/a:1009692902805. Apoptosis. 2000. PMID: 11256887 Review.

3

Activation of virus-specific memory B cells in the absence of T cell help.

Hebeis BJ, Klenovsek K, Rohwer P, Ritter U, Schneider A, Mach M, Winkler TH. Hebeis BJ, et al. Among authors: winkler th. J Exp Med. 2004 Feb 16;199(4):593-602. doi: 10.1084/jem.20030091. Epub 2004 Feb 9. J Exp Med. 2004. PMID: 14769849 Free PMC article.

4

Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components.

Galler GR, Mundt C, Parker M, Pelanda R, Mårtensson IL, Winkler TH. Galler GR, et al. Among authors: winkler th. J Exp Med. 2004 Jun 7;199(11):1523-32. doi: 10.1084/jem.20031523. Epub 2004 Jun 1. J Exp Med. 2004. PMID: 15173209 Free PMC article.

5

Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.

Hoffmann A, Kerr S, Jellusova J, Zhang J, Weisel F, Wellmann U, Winkler TH, Kneitz B, Crocker PR, Nitschke L. Hoffmann A, et al. Among authors: winkler th. Nat Immunol. 2007 Jul;8(7):695-704. doi: 10.1038/ni1480. Epub 2007 Jun 17. Nat Immunol. 2007. PMID: 17572677

6

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis.

Neubert K, Meister S, Moser K, Weisel F, Maseda D, Amann K, Wiethe C, Winkler TH, Kalden JR, Manz RA, Voll RE. Neubert K, et al. Among authors: winkler th. Nat Med. 2008 Jul;14(7):748-55. doi: 10.1038/nm1763. Epub 2008 Jun 8. Nat Med. 2008. PMID: 18542049

7

CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.

Jellusova J, Wellmann U, Amann K, Winkler TH, Nitschke L. Jellusova J, et al. Among authors: winkler th. J Immunol. 2010 Apr 1;184(7):3618-27. doi: 10.4049/jimmunol.0902711. Epub 2010 Mar 3. J Immunol. 2010. PMID: 20200274

8

Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling.

Ackermann JA, Radtke D, Maurberger A, Winkler TH, Nitschke L. Ackermann JA, et al. Among authors: winkler th. EMBO J. 2011 Apr 20;30(8):1621-33. doi: 10.1038/emboj.2011.74. Epub 2011 Mar 22. EMBO J. 2011. PMID: 21427701 Free PMC article.

9

A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.

Brenner S, Drewel D, Steinbart T, Weisel F, Härtel E, Pötzsch S, Welzel H, Brandl A, Yu P, Mudde GC, Schweizer A, Nitschke L, Winkler TH. Brenner S, et al. Among authors: winkler th. EMBO J. 2011 May 27;30(13):2705-18. doi: 10.1038/emboj.2011.168. EMBO J. 2011. PMID: 21623346 Free PMC article.

10

The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.

Hutzler S, Özgör L, Naito-Matsui Y, Kläsener K, Winkler TH, Reth M, Nitschke L. Hutzler S, et al. Among authors: winkler th. J Immunol. 2014 Jun 1;192(11):5406-14. doi: 10.4049/jimmunol.1302875. Epub 2014 Apr 30. J Immunol. 2014. PMID: 24790146 Free article.

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