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pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation.
Nuhn L, Vanparijs N, De Beuckelaer A, Lybaert L, Verstraete G, Deswarte K, Lienenklaus S, Shukla NM, Salyer AC, Lambrecht BN, Grooten J, David SA, De Koker S, De Geest BG. Nuhn L, et al. Among authors: lienenklaus s. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8098-103. doi: 10.1073/pnas.1600816113. Epub 2016 Jul 5. Proc Natl Acad Sci U S A. 2016. PMID: 27382168 Free PMC article.
Immunoglobulins drive terminal maturation of splenic dendritic cells.
Zietara N, Łyszkiewicz M, Puchałka J, Pei G, Gutierrez MG, Lienenklaus S, Hobeika E, Reth M, Martins dos Santos VA, Krueger A, Weiss S. Zietara N, et al. Among authors: lienenklaus s. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2282-7. doi: 10.1073/pnas.1210654110. Epub 2013 Jan 23. Proc Natl Acad Sci U S A. 2013. PMID: 23345431 Free PMC article.
Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses.
De Beuckelaer A, Pollard C, Van Lint S, Roose K, Van Hoecke L, Naessens T, Udhayakumar VK, Smet M, Sanders N, Lienenklaus S, Saelens X, Weiss S, Vanham G, Grooten J, De Koker S. De Beuckelaer A, et al. Among authors: lienenklaus s. Mol Ther. 2016 Nov;24(11):2012-2020. doi: 10.1038/mt.2016.161. Epub 2016 Aug 10. Mol Ther. 2016. PMID: 27506450 Free PMC article.
Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide.
Udhayakumar VK, De Beuckelaer A, McCaffrey J, McCrudden CM, Kirschman JL, Vanover D, Van Hoecke L, Roose K, Deswarte K, De Geest BG, Lienenklaus S, Santangelo PJ, Grooten J, McCarthy HO, De Koker S. Udhayakumar VK, et al. Among authors: lienenklaus s. Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201601412. Epub 2017 Apr 24. Adv Healthc Mater. 2017. PMID: 28436620
Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.
Van der Jeught K, De Koker S, Bialkowski L, Heirman C, Tjok Joe P, Perche F, Maenhout S, Bevers S, Broos K, Deswarte K, Malard V, Hammad H, Baril P, Benvegnu T, Jaffrès PA, Kooijmans SAA, Schiffelers R, Lienenklaus S, Midoux P, Pichon C, Breckpot K, Thielemans K. Van der Jeught K, et al. Among authors: lienenklaus s. ACS Nano. 2018 Oct 23;12(10):9815-9829. doi: 10.1021/acsnano.8b00966. Epub 2018 Oct 1. ACS Nano. 2018. PMID: 30256609 Free article.
112 results