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Page 1
12(S)-HETE increases intracellular Ca(2+) in lymph-endothelial cells disrupting their barrier function in vitro; stabilization by clinical drugs impairing calcium supply.
Nguyen CH, Brenner S, Huttary N, Li Y, Atanasov AG, Dirsch VM, Holzner S, Stadler S, Riha J, Krieger S, Milovanovic D, Fristiohardy A, Simonitsch-Klupp I, Dolznig H, Saiko P, Szekeres T, Giessrigl B, Jäger W, Krupitza G. Nguyen CH, et al. Among authors: dolznig h. Cancer Lett. 2016 Sep 28;380(1):174-83. doi: 10.1016/j.canlet.2016.06.022. Epub 2016 Jul 4. Cancer Lett. 2016. PMID: 27390016
Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse.
Kerjaschki D, Bago-Horvath Z, Rudas M, Sexl V, Schneckenleithner C, Wolbank S, Bartel G, Krieger S, Kalt R, Hantusch B, Keller T, Nagy-Bojarszky K, Huttary N, Raab I, Lackner K, Krautgasser K, Schachner H, Kaserer K, Rezar S, Madlener S, Vonach C, Davidovits A, Nosaka H, Hämmerle M, Viola K, Dolznig H, Schreiber M, Nader A, Mikulits W, Gnant M, Hirakawa S, Detmar M, Alitalo K, Nijman S, Offner F, Maier TJ, Steinhilber D, Krupitza G. Kerjaschki D, et al. Among authors: dolznig h. J Clin Invest. 2011 May;121(5):2000-12. doi: 10.1172/JCI44751. Epub 2011 Apr 11. J Clin Invest. 2011. PMID: 21540548 Free PMC article.
NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells.
Vonach C, Viola K, Giessrigl B, Huttary N, Raab I, Kalt R, Krieger S, Vo TP, Madlener S, Bauer S, Marian B, Hämmerle M, Kretschy N, Teichmann M, Hantusch B, Stary S, Unger C, Seelinger M, Eger A, Mader R, Jäger W, Schmidt W, Grusch M, Dolznig H, Mikulits W, Krupitza G. Vonach C, et al. Among authors: dolznig h. Br J Cancer. 2011 Jul 12;105(2):263-71. doi: 10.1038/bjc.2011.194. Epub 2011 May 31. Br J Cancer. 2011. PMID: 21629247 Free PMC article.
In vitro cell migration and invasion assays.
Kramer N, Walzl A, Unger C, Rosner M, Krupitza G, Hengstschläger M, Dolznig H. Kramer N, et al. Among authors: dolznig h. Mutat Res. 2013 Jan-Mar;752(1):10-24. doi: 10.1016/j.mrrev.2012.08.001. Epub 2012 Aug 23. Mutat Res. 2013. PMID: 22940039 Review.
Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion.
Viola K, Kopf S, Huttary N, Vonach C, Kretschy N, Teichmann M, Giessrigl B, Raab I, Stary S, Krieger S, Keller T, Bauer S, Hantusch B, Szekeres T, de Martin R, Jäger W, Mikulits W, Dolznig H, Krupitza G, Grusch M. Viola K, et al. Among authors: dolznig h. Br J Cancer. 2013 Feb 19;108(3):564-9. doi: 10.1038/bjc.2012.485. Epub 2012 Oct 23. Br J Cancer. 2013. PMID: 23093227 Free PMC article.
The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.
Unger C, Popescu R, Giessrigl B, Laimer D, Heider S, Seelinger M, Diaz R, Wallnöfer B, Egger G, Hassler M, Knöfler M, Saleh L, Sahin E, Grusch M, Fritzer-Szekeres M, Dolznig H, Frisch R, Kenner L, Kopp B, Krupitza G. Unger C, et al. Among authors: dolznig h. Int J Oncol. 2013 Jan;42(1):338-48. doi: 10.3892/ijo.2012.1690. Epub 2012 Nov 6. Int J Oncol. 2013. PMID: 23135783
In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen.
Kretschy N, Teichmann M, Kopf S, Atanasov AG, Saiko P, Vonach C, Viola K, Giessrigl B, Huttary N, Raab I, Krieger S, Jäger W, Szekeres T, Nijman SM, Mikulits W, Dirsch VM, Dolznig H, Grusch M, Krupitza G. Kretschy N, et al. Among authors: dolznig h. Br J Cancer. 2013 Feb 19;108(3):570-8. doi: 10.1038/bjc.2012.580. Epub 2013 Jan 8. Br J Cancer. 2013. PMID: 23299527 Free PMC article.
Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis.
Viola K, Kopf S, Rarova L, Jarukamjorn K, Kretschy N, Teichmann M, Vonach C, Atanasov AG, Giessrigl B, Huttary N, Raab I, Krieger S, Strnad M, de Martin R, Saiko P, Szekeres T, Knasmüller S, Dirsch VM, Jäger W, Grusch M, Dolznig H, Mikulits W, Krupitza G. Viola K, et al. Among authors: dolznig h. Arch Toxicol. 2013 Jul;87(7):1301-12. doi: 10.1007/s00204-013-1028-2. Epub 2013 Mar 17. Arch Toxicol. 2013. PMID: 23503627
In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.
Kopf S, Viola K, Atanasov AG, Jarukamjorn K, Rarova L, Kretschy N, Teichmann M, Vonach C, Saiko P, Giessrigl B, Huttary N, Raab I, Krieger S, Schumacher M, Diederich M, Strnad M, de Martin R, Szekeres T, Jäger W, Dirsch VM, Mikulits W, Grusch M, Dolznig H, Krupitza G. Kopf S, et al. Among authors: dolznig h. Arch Toxicol. 2013 Oct;87(10):1851-61. doi: 10.1007/s00204-013-1045-1. Epub 2013 Mar 30. Arch Toxicol. 2013. PMID: 23543012
96 results