McClements ME - Search Results

1

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice.

Barnea-Cramer AO, Wang W, Lu SJ, Singh MS, Luo C, Huo H, McClements ME, Barnard AR, MacLaren RE, Lanza R. Barnea-Cramer AO, et al. Among authors: mcclements me. Sci Rep. 2016 Jul 13;6:29784. doi: 10.1038/srep29784. Sci Rep. 2016. PMID: 27405580 Free PMC article.

2

Tetradecanoylphorbol-13-acetate (TPA) significantly increases AAV2/5 transduction of human neuronal cells in vitro.

You Q, Brown LA, McClements M, Hankins MW, Maclaren RE. You Q, et al. Exp Eye Res. 2012 Apr;97(1):148-53. doi: 10.1016/j.exer.2011.12.009. Epub 2011 Dec 16. Exp Eye Res. 2012. PMID: 22197749

3

Gene therapy for retinal disease.

McClements ME, MacLaren RE. McClements ME, et al. Transl Res. 2013 Apr;161(4):241-54. doi: 10.1016/j.trsl.2012.12.007. Epub 2013 Jan 8. Transl Res. 2013. PMID: 23305707 Free PMC article. Review.

4

Variations in opsin coding sequences cause x-linked cone dysfunction syndrome with myopia and dichromacy.

McClements M, Davies WI, Michaelides M, Young T, Neitz M, MacLaren RE, Moore AT, Hunt DM. McClements M, et al. Invest Ophthalmol Vis Sci. 2013 Feb 15;54(2):1361-9. doi: 10.1167/iovs.12-11156. Invest Ophthalmol Vis Sci. 2013. PMID: 23322568 Free PMC article.

5

X-linked cone dystrophy and colour vision deficiency arising from a missense mutation in a hybrid L/M cone opsin gene.

McClements M, Davies WI, Michaelides M, Carroll J, Rha J, Mollon JD, Neitz M, MacLaren RE, Moore AT, Hunt DM. McClements M, et al. Vision Res. 2013 Mar 22;80:41-50. doi: 10.1016/j.visres.2012.12.012. Epub 2013 Jan 18. Vision Res. 2013. PMID: 23337435 Free PMC article.

6

A fragmented adeno-associated viral dual vector strategy for treatment of diseases caused by mutations in large genes leads to expression of hybrid transcripts.

McClements ME, Charbel Issa P, Blouin V, MacLaren RE. McClements ME, et al. J Genet Syndr Gene Ther. 2016 Nov 14;7(5):311. doi: 10.4172/2157-7412.1000311. J Genet Syndr Gene Ther. 2016. PMID: 28239514 Free PMC article.

7

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina.

Patrício MI, Barnard AR, Orlans HO, McClements ME, MacLaren RE. Patrício MI, et al. Among authors: mcclements me. Mol Ther Nucleic Acids. 2017 Mar 17;6:198-208. doi: 10.1016/j.omtn.2016.12.006. Epub 2016 Dec 31. Mol Ther Nucleic Acids. 2017. PMID: 28325286 Free PMC article.

8

Codon-Optimized RPGR Improves Stability and Efficacy of AAV8 Gene Therapy in Two Mouse Models of X-Linked Retinitis Pigmentosa.

Fischer MD, McClements ME, Martinez-Fernandez de la Camara C, Bellingrath JS, Dauletbekov D, Ramsden SC, Hickey DG, Barnard AR, MacLaren RE. Fischer MD, et al. Among authors: mcclements me. Mol Ther. 2017 Aug 2;25(8):1854-1865. doi: 10.1016/j.ymthe.2017.05.005. Epub 2017 May 24. Mol Ther. 2017. PMID: 28549772 Free PMC article.

9

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.

Hickey DG, Edwards TL, Barnard AR, Singh MS, de Silva SR, McClements ME, Flannery JG, Hankins MW, MacLaren RE. Hickey DG, et al. Among authors: mcclements me. Gene Ther. 2017 Dec;24(12):787-800. doi: 10.1038/gt.2017.85. Epub 2017 Nov 16. Gene Ther. 2017. PMID: 28872643 Free PMC article.

10

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.

De Silva SR, Barnard AR, Hughes S, Tam SKE, Martin C, Singh MS, Barnea-Cramer AO, McClements ME, During MJ, Peirson SN, Hankins MW, MacLaren RE. De Silva SR, et al. Among authors: mcclements me. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11211-11216. doi: 10.1073/pnas.1701589114. Epub 2017 Oct 2. Proc Natl Acad Sci U S A. 2017. PMID: 28973921 Free PMC article.

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