Hruska MW - Search Results

1

CYP2C19 Genotype-Dependent Pharmacokinetic Drug Interaction Between Voriconazole and Ritonavir-Boosted Atazanavir in Healthy Subjects.

Zhu L, Brüggemann RJ, Uy J, Colbers A, Hruska MW, Chung E, Sims K, Vakkalagadda B, Xu X, van Schaik RH, Burger DM, Bertz RJ. Zhu L, et al. Among authors: hruska mw. J Clin Pharmacol. 2017 Feb;57(2):235-246. doi: 10.1002/jcph.798. Epub 2016 Aug 23. J Clin Pharmacol. 2017. PMID: 27432796

2

Pharmacokinetic interactions between BMS-626529, the active moiety of the HIV-1 attachment inhibitor prodrug BMS-663068, and ritonavir or ritonavir-boosted atazanavir in healthy subjects.

Zhu L, Hruska M, Hwang C, Shah V, Furlong M, Hanna GJ, Bertz R, Landry IS. Zhu L, et al. Antimicrob Agents Chemother. 2015 Jul;59(7):3816-22. doi: 10.1128/AAC.04914-14. Epub 2015 Apr 13. Antimicrob Agents Chemother. 2015. PMID: 25870057 Free PMC article. Clinical Trial.

3

The pharmacokinetics of peginterferon lambda-1a following single dose administration to subjects with impaired renal function.

Hruska MW, Adamczyk R, Colston E, Hesney M, Stonier M, Myler H, Bertz R. Hruska MW, et al. Br J Clin Pharmacol. 2015 Sep;80(3):515-24. doi: 10.1111/bcp.12634. Epub 2015 Jul 22. Br J Clin Pharmacol. 2015. PMID: 25807956 Free PMC article. Clinical Trial.

4

Model-Based Phase 3 Dose Selection for HIV-1 Attachment Inhibitor Prodrug BMS-663068 in HIV-1-Infected Patients: Population Pharmacokinetics/Pharmacodynamics of the Active Moiety, BMS-626529.

Landry I, Zhu L, Abu Tarif M, Hruska M, Sadler BM, Pitsiu M, Joshi S, Hanna GJ, Lataillade M, Boulton DW, Bertz RJ. Landry I, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2782-9. doi: 10.1128/AAC.02503-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26902761 Free PMC article. Clinical Trial.

5

Derivation of Phase 3 dosing for peginterferon lambda-1a in chronic hepatitis C, Part 2: Exposure-response analyses for efficacy and safety variables.

Hruska M, Wang X, Chan P, Ahmad A, Freeman J, Horga MA, Hillson J, Kansra V, Lopez-Talavera JC. Hruska M, et al. J Clin Pharmacol. 2015 Jan;55(1):73-80. doi: 10.1002/jcph.361. Epub 2014 Jul 24. J Clin Pharmacol. 2015. PMID: 25042797 Clinical Trial.

6

Population Pharmacokinetics and Exposure - Safety Analyses of Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma.

Wang X, Ludwig EA, Passarell J, Bello A, Roy A, Hruska MW. Wang X, et al. Among authors: hruska mw. J Clin Pharmacol. 2019 Mar;59(3):364-373. doi: 10.1002/jcph.1324. Epub 2018 Oct 19. J Clin Pharmacol. 2019. PMID: 30339279

7

The effect of trimethoprim on CYP2C8 mediated rosiglitazone metabolism in human liver microsomes and healthy subjects.

Hruska MW, Amico JA, Langaee TY, Ferrell RE, Fitzgerald SM, Frye RF. Hruska MW, et al. Br J Clin Pharmacol. 2005 Jan;59(1):70-9. doi: 10.1111/j.1365-2125.2005.02263.x. Br J Clin Pharmacol. 2005. PMID: 15606443 Free PMC article. Clinical Trial.

8

Effect of St John's wort on imatinib mesylate pharmacokinetics.

Frye RF, Fitzgerald SM, Lagattuta TF, Hruska MW, Egorin MJ. Frye RF, et al. Among authors: hruska mw. Clin Pharmacol Ther. 2004 Oct;76(4):323-9. doi: 10.1016/j.clpt.2004.06.007. Clin Pharmacol Ther. 2004. PMID: 15470331 Clinical Trial.

9

Population pharmacokinetics analysis of nivolumab in Asian and non-Asian patients with gastric and gastro-esophageal junction cancers.

Osawa M, Hasegawa M, Bello A, Roy A, Hruska MW. Osawa M, et al. Among authors: hruska mw. Cancer Chemother Pharmacol. 2019 Apr;83(4):705-715. doi: 10.1007/s00280-019-03771-z. Epub 2019 Jan 21. Cancer Chemother Pharmacol. 2019. PMID: 30666395

10

Assessment of nivolumab benefit-risk profile of a 240-mg flat dose relative to a 3-mg/kg dosing regimen in patients with advanced tumors.

Zhao X, Suryawanshi S, Hruska M, Feng Y, Wang X, Shen J, Vezina HE, McHenry MB, Waxman IM, Achanta A, Bello A, Roy A, Agrawal S. Zhao X, et al. Ann Oncol. 2017 Aug 1;28(8):2002-2008. doi: 10.1093/annonc/mdx235. Ann Oncol. 2017. PMID: 28520840 Free PMC article.

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