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Inhibition of T-cell activation by the CTLA4-Fc Abatacept is sufficient to ameliorate proteinuric kidney disease.
Herrera M, Söderberg M, Sabirsh A, Valastro B, Mölne J, Santamaria B, Valverde AM, Guionaud S, Heasman S, Bigley A, Jermutus L, Rondinone C, Coghlan M, Baker D, Quinn CM. Herrera M, et al. Among authors: santamaria b. Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F748-F759. doi: 10.1152/ajprenal.00179.2016. Epub 2016 Jul 20. Am J Physiol Renal Physiol. 2017. PMID: 27440778 Free article.
IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes.
Santamaria B, Marquez E, Lay A, Carew RM, González-Rodríguez Á, Welsh GI, Ni L, Hale LJ, Ortiz A, Saleem MA, Brazil DP, Coward RJ, Valverde ÁM. Santamaria B, et al. Biochim Biophys Acta. 2015 Dec;1853(12):3224-34. doi: 10.1016/j.bbamcr.2015.09.020. Epub 2015 Sep 16. Biochim Biophys Acta. 2015. PMID: 26384875 Free article.
Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.
Pilar Valdecantos M, Prieto-Hontoria PL, Pardo V, Módol T, Santamaría B, Weber M, Herrero L, Serra D, Muntané J, Cuadrado A, Moreno-Aliaga MJ, Alfredo Martínez J, Valverde ÁM. Pilar Valdecantos M, et al. Among authors: santamaria b. Free Radic Biol Med. 2015 Jul;84:263-278. doi: 10.1016/j.freeradbiomed.2015.03.019. Epub 2015 Apr 1. Free Radic Biol Med. 2015. PMID: 25841776
Trail and kidney disease.
Lorz C, Benito A, Ucero AC, Santamaría B, Ortiz A. Lorz C, et al. Among authors: santamaria b. Front Biosci (Landmark Ed). 2009 Jan 1;14(10):3740-9. doi: 10.2741/3485. Front Biosci (Landmark Ed). 2009. PMID: 19273307 Free article. Review.
The death ligand TRAIL in diabetic nephropathy.
Lorz C, Benito-Martín A, Boucherot A, Ucero AC, Rastaldi MP, Henger A, Armelloni S, Santamaría B, Berthier CC, Kretzler M, Egido J, Ortiz A. Lorz C, et al. Among authors: santamaria b. J Am Soc Nephrol. 2008 May;19(5):904-14. doi: 10.1681/ASN.2007050581. Epub 2008 Feb 20. J Am Soc Nephrol. 2008. PMID: 18287563 Free PMC article.
Mechanisms of renal apoptosis in health and disease.
Sanz AB, Santamaría B, Ruiz-Ortega M, Egido J, Ortiz A. Sanz AB, et al. Among authors: santamaria b. J Am Soc Nephrol. 2008 Sep;19(9):1634-42. doi: 10.1681/ASN.2007121336. Epub 2008 Jul 16. J Am Soc Nephrol. 2008. PMID: 18632846 Review.
TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-dependent proliferation of cultured renal fibroblast.
Ucero AC, Benito-Martin A, Fuentes-Calvo I, Santamaria B, Blanco J, Lopez-Novoa JM, Ruiz-Ortega M, Egido J, Burkly LC, Martinez-Salgado C, Ortiz A. Ucero AC, et al. Among authors: santamaria b. Biochim Biophys Acta. 2013 Oct;1832(10):1744-55. doi: 10.1016/j.bbadis.2013.05.032. Epub 2013 Jun 6. Biochim Biophys Acta. 2013. PMID: 23748045 Free article.
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