Schmidt HHHW - Search Results

1

NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis.

Di Marco E, Gray SP, Kennedy K, Szyndralewiez C, Lyle AN, Lassègue B, Griendling KK, Cooper ME, Schmidt HHHW, Jandeleit-Dahm KAM. Di Marco E, et al. Among authors: schmidt hhhw. Free Radic Biol Med. 2016 Aug;97:556-567. doi: 10.1016/j.freeradbiomed.2016.07.013. Epub 2016 Jul 19. Free Radic Biol Med. 2016. PMID: 27445103 Free PMC article.

2

NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis.

Gray SP, Di Marco E, Okabe J, Szyndralewiez C, Heitz F, Montezano AC, de Haan JB, Koulis C, El-Osta A, Andrews KL, Chin-Dusting JP, Touyz RM, Wingler K, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Gray SP, et al. Circulation. 2013 May 7;127(18):1888-902. doi: 10.1161/CIRCULATIONAHA.112.132159. Epub 2013 Apr 5. Circulation. 2013. PMID: 23564668

3

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.

Jha JC, Gray SP, Barit D, Okabe J, El-Osta A, Namikoshi T, Thallas-Bonke V, Wingler K, Szyndralewiez C, Heitz F, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Jha JC, et al. J Am Soc Nephrol. 2014 Jun;25(6):1237-54. doi: 10.1681/ASN.2013070810. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511132 Free PMC article.

4

Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy.

Jha JC, Thallas-Bonke V, Banal C, Gray SP, Chow BS, Ramm G, Quaggin SE, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Jha JC, et al. Diabetologia. 2016 Feb;59(2):379-89. doi: 10.1007/s00125-015-3796-0. Epub 2015 Oct 28. Diabetologia. 2016. PMID: 26508318 Free PMC article.

5

Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.

Gray SP, Di Marco E, Kennedy K, Chew P, Okabe J, El-Osta A, Calkin AC, Biessen EA, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Gray SP, et al. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):295-307. doi: 10.1161/ATVBAHA.115.307012. Epub 2015 Dec 29. Arterioscler Thromb Vasc Biol. 2016. PMID: 26715682

6

Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice.

Di Marco E, Gray SP, Chew P, Kennedy K, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Di Marco E, et al. Clin Sci (Lond). 2016 Aug 1;130(15):1363-74. doi: 10.1042/CS20160249. Epub 2016 May 17. Clin Sci (Lond). 2016. PMID: 27190136

7

Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease.

Gray SP, Jha JC, Kennedy K, van Bommel E, Chew P, Szyndralewiez C, Touyz RM, Schmidt HHHW, Cooper ME, Jandeleit-Dahm KAM. Gray SP, et al. Among authors: schmidt hhhw. Diabetologia. 2017 May;60(5):927-937. doi: 10.1007/s00125-017-4215-5. Epub 2017 Feb 3. Diabetologia. 2017. PMID: 28160092

8

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production.

Dikalov SI, Dikalova AE, Bikineyeva AT, Schmidt HH, Harrison DG, Griendling KK. Dikalov SI, et al. Free Radic Biol Med. 2008 Nov 1;45(9):1340-51. doi: 10.1016/j.freeradbiomed.2008.08.013. Epub 2008 Aug 16. Free Radic Biol Med. 2008. PMID: 18760347 Free PMC article.

9

Endothelial reactive oxygen-forming NADPH oxidase 5 is a possible player in diabetic aortic aneurysm but not atherosclerosis.

Ho F, Watson AMD, Elbatreek MH, Kleikers PWM, Khan W, Sourris KC, Dai A, Jha J, Schmidt HHHW, Jandeleit-Dahm KAM. Ho F, et al. Among authors: schmidt hhhw. Sci Rep. 2022 Jul 7;12(1):11570. doi: 10.1038/s41598-022-15706-5. Sci Rep. 2022. PMID: 35798762 Free PMC article.

10

Reactive Oxygen Comes of Age: Mechanism-Based Therapy of Diabetic End-Organ Damage.

Elbatreek MH, Pachado MP, Cuadrado A, Jandeleit-Dahm K, Schmidt HHHW. Elbatreek MH, et al. Among authors: schmidt hhhw. Trends Endocrinol Metab. 2019 May;30(5):312-327. doi: 10.1016/j.tem.2019.02.006. Epub 2019 Mar 27. Trends Endocrinol Metab. 2019. PMID: 30928357 Free article. Review.

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