Wanker EE - Search Results

1

Amyloid-β(1-42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity.

Jin S, Kedia N, Illes-Toth E, Haralampiev I, Prisner S, Herrmann A, Wanker EE, Bieschke J. Jin S, et al. Among authors: wanker ee. J Biol Chem. 2016 Sep 9;291(37):19590-606. doi: 10.1074/jbc.M115.691840. Epub 2016 Jul 25. J Biol Chem. 2016. PMID: 27458018 Free PMC article.

2

Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations.

Wanker EE. Wanker EE. Biol Chem. 2000 Sep-Oct;381(9-10):937-42. doi: 10.1515/BC.2000.114. Biol Chem. 2000. PMID: 11076024 Review.

3

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease.

Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE. Busch A, et al. Among authors: wanker ee. J Biol Chem. 2003 Oct 17;278(42):41452-61. doi: 10.1074/jbc.M303354200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888569 Free article.

4

Interaction of huntingtin fragments with brain membranes--clues to early dysfunction in Huntington's disease.

Suopanki J, Götz C, Lutsch G, Schiller J, Harjes P, Herrmann A, Wanker EE. Suopanki J, et al. Among authors: wanker ee. J Neurochem. 2006 Feb;96(3):870-84. doi: 10.1111/j.1471-4159.2005.03620.x. Epub 2006 Jan 9. J Neurochem. 2006. PMID: 16405500 Free article.

5

Alpha-synuclein selectively binds to anionic phospholipids embedded in liquid-disordered domains.

Stöckl M, Fischer P, Wanker E, Herrmann A. Stöckl M, et al. J Mol Biol. 2008 Feb 1;375(5):1394-404. doi: 10.1016/j.jmb.2007.11.051. Epub 2007 Nov 22. J Mol Biol. 2008. PMID: 18082181

6

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.

Ehrnhoefer DE, Bieschke J, Boeddrich A, Herbst M, Masino L, Lurz R, Engemann S, Pastore A, Wanker EE. Ehrnhoefer DE, et al. Among authors: wanker ee. Nat Struct Mol Biol. 2008 Jun;15(6):558-66. doi: 10.1038/nsmb.1437. Epub 2008 May 30. Nat Struct Mol Biol. 2008. PMID: 18511942

7

EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity.

Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE. Bieschke J, et al. Among authors: wanker ee. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7710-5. doi: 10.1073/pnas.0910723107. Epub 2010 Apr 12. Proc Natl Acad Sci U S A. 2010. PMID: 20385841 Free PMC article.

8

670 nm laser light and EGCG complementarily reduce amyloid-β aggregates in human neuroblastoma cells: basis for treatment of Alzheimer's disease?

Sommer AP, Bieschke J, Friedrich RP, Zhu D, Wanker EE, Fecht HJ, Mereles D, Hunstein W. Sommer AP, et al. Among authors: wanker ee. Photomed Laser Surg. 2012 Jan;30(1):54-60. doi: 10.1089/pho.2011.3073. Epub 2011 Oct 26. Photomed Laser Surg. 2012. PMID: 22029866

9

Black tea theaflavins inhibit formation of toxic amyloid-β and α-synuclein fibrils.

Grelle G, Otto A, Lorenz M, Frank RF, Wanker EE, Bieschke J. Grelle G, et al. Among authors: wanker ee. Biochemistry. 2011 Dec 13;50(49):10624-36. doi: 10.1021/bi2012383. Epub 2011 Nov 16. Biochemistry. 2011. PMID: 22054421

10

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.

Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez del Amo JM, Grüning BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Fändrich M, Frank RF, Reif B, Günther S, Walsh DM, Wanker EE. Bieschke J, et al. Among authors: wanker ee. Nat Chem Biol. 2011 Nov 20;8(1):93-101. doi: 10.1038/nchembio.719. Nat Chem Biol. 2011. PMID: 22101602

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