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A phase I first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone in patients with progressive multiple myeloma.
Metselaar J, Lammers T, Boquoi A, Fenk R, Testaquadra F, Schemionek M, Kiessling F, Isfort S, Wilop S, Crysandt M. Metselaar J, et al. Drug Deliv Transl Res. 2023 Apr;13(4):915-923. doi: 10.1007/s13346-022-01268-6. Epub 2023 Jan 2. Drug Deliv Transl Res. 2023. PMID: 36592287 Free PMC article. Clinical Trial.
Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis.
van der Valk FM, Schulte DM, Meiler S, Tang J, Zheng KH, Van den Bossche J, Seijkens T, Laudes M, de Winther M, Lutgens E, Alaarg A, Metselaar JM, Dallinga-Thie GM, Mulder WJ, Stroes ES, Hamers AA. van der Valk FM, et al. Among authors: metselaar jm. Nanomedicine. 2016 Aug;12(6):1463-70. doi: 10.1016/j.nano.2016.02.022. Epub 2016 Mar 23. Nanomedicine. 2016. PMID: 27015770
Local delivery of liposomal prednisolone leads to an anti-inflammatory profile in renal ischaemia-reperfusion injury in the rat.
van Alem CMA, Boonstra M, Prins J, Bezhaeva T, van Essen MF, Ruben JM, Vahrmeijer AL, van der Veer EP, de Fijter JW, Reinders ME, Meijer O, Metselaar JM, van Kooten C, Rotmans JI. van Alem CMA, et al. Among authors: metselaar jm. Nephrol Dial Transplant. 2018 Jan 1;33(1):44-53. doi: 10.1093/ndt/gfx204. Nephrol Dial Transplant. 2018. PMID: 28992069
ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer.
Kuninty PR, Bansal R, De Geus SWL, Mardhian DF, Schnittert J, van Baarlen J, Storm G, Bijlsma MF, van Laarhoven HW, Metselaar JM, Kuppen PJK, Vahrmeijer AL, Östman A, Sier CFM, Prakash J. Kuninty PR, et al. Among authors: metselaar jm. Sci Adv. 2019 Sep 4;5(9):eaax2770. doi: 10.1126/sciadv.aax2770. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31517053 Free PMC article.
Liposomal Delivery Improves the Efficacy of Prednisolone to Attenuate Renal Inflammation in a Mouse Model of Acute Renal Allograft Rejection.
van Alem CMA, Schmidbauer M, Rong S, Derlin K, Schmitz J, Bräsen JH, Thorenz A, Chen R, Ruben JM, Winter EM, Schilperoort M, Kooijman S, Lalai RA, Metselaar JM, Klemann C, Meier M, van Kooten C, Gueler F, Rotmans JI. van Alem CMA, et al. Among authors: metselaar jm. Transplantation. 2020 Apr;104(4):744-753. doi: 10.1097/TP.0000000000003060. Transplantation. 2020. PMID: 31929419 Free PMC article.
A Randomized Trial of Liposomal Prednisolone (LIPMAT) to Enhance Radiocephalic Fistula Maturation: A Pilot Study.
Voorzaat BM, van der Bogt KEA, Bezhaeva T, van Schaik J, Eefting D, van der Putten K, van Nieuwenhuizen RC, Groeneveld JO, Hoogeveen EK, van der Meer IM, Statius van Eps RG, Vogt L, Huisman L, Gabreëls BATF, Boom H, Verburgh CA, Boon D, Metselaar JM, Weijmer MC, Rotmans JI. Voorzaat BM, et al. Among authors: metselaar jm. Kidney Int Rep. 2020 Jun 5;5(8):1327-1332. doi: 10.1016/j.ekir.2020.05.030. eCollection 2020 Aug. Kidney Int Rep. 2020. PMID: 32775836 Free PMC article. No abstract available.
Recent Advances in Liposomal-Based Anti-Inflammatory Therapy.
van Alem CMA, Metselaar JM, van Kooten C, Rotmans JI. van Alem CMA, et al. Among authors: metselaar jm. Pharmaceutics. 2021 Jul 1;13(7):1004. doi: 10.3390/pharmaceutics13071004. Pharmaceutics. 2021. PMID: 34371695 Free PMC article. Review.
95 results