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Page 1
NTRK3 kinase fusions in Spitz tumours.
Yeh I, Tee MK, Botton T, Shain AH, Sparatta AJ, Gagnon A, Vemula SS, Garrido MC, Nakamaru K, Isoyama T, McCalmont TH, LeBoit PE, Bastian BC. Yeh I, et al. Among authors: sparatta aj. J Pathol. 2016 Nov;240(3):282-290. doi: 10.1002/path.4775. J Pathol. 2016. PMID: 27477320 Free PMC article.
Ambiguous melanocytic tumors with loss of 3p21.
Yeh I, Mully TW, Wiesner T, Vemula SS, Mirza SA, Sparatta AJ, McCalmont TH, Bastian BC, LeBoit PE. Yeh I, et al. Among authors: sparatta aj. Am J Surg Pathol. 2014 Aug;38(8):1088-95. doi: 10.1097/PAS.0000000000000209. Am J Surg Pathol. 2014. PMID: 24705312 Free PMC article.
Activating MET kinase rearrangements in melanoma and Spitz tumours.
Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, de la Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, LeBoit PE, Bastian BC. Yeh I, et al. Among authors: sparatta aj. Nat Commun. 2015 May 27;6:7174. doi: 10.1038/ncomms8174. Nat Commun. 2015. PMID: 26013381 Free PMC article.
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy.
Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC. Botton T, et al. Pigment Cell Melanoma Res. 2013 Nov;26(6):845-51. doi: 10.1111/pcmr.12148. Epub 2013 Aug 19. Pigment Cell Melanoma Res. 2013. PMID: 23890088 Free PMC article.
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC. Wiesner T, et al. Nat Commun. 2014;5:3116. doi: 10.1038/ncomms4116. Nat Commun. 2014. PMID: 24445538 Free PMC article.