Lieberman RL - Search Results

1

Lessons from an α-Helical Membrane Enzyme: Expression, Purification, and Detergent Optimization for Biophysical and Structural Characterization.

Johnson JL, Kalyoncu S, Lieberman RL. Johnson JL, et al. Among authors: lieberman rl. Methods Mol Biol. 2016;1432:281-301. doi: 10.1007/978-1-4939-3637-3_18. Methods Mol Biol. 2016. PMID: 27485343

2

Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin.

Orwig SD, Perry CW, Kim LY, Turnage KC, Zhang R, Vollrath D, Schmidt-Krey I, Lieberman RL. Orwig SD, et al. Among authors: lieberman rl. J Mol Biol. 2012 Aug 10;421(2-3):242-55. doi: 10.1016/j.jmb.2011.12.016. Epub 2011 Dec 13. J Mol Biol. 2012. PMID: 22197377 Free PMC article.

3

Determination of soluble and membrane protein structures by X-ray crystallography.

Lieberman RL, Peek ME, Watkins JD. Lieberman RL, et al. Methods Mol Biol. 2013;955:475-93. doi: 10.1007/978-1-62703-176-9_25. Methods Mol Biol. 2013. PMID: 23132076

4

The glaucoma-associated olfactomedin domain of myocilin forms polymorphic fibrils that are constrained by partial unfolding and peptide sequence.

Hill SE, Donegan RK, Lieberman RL. Hill SE, et al. Among authors: lieberman rl. J Mol Biol. 2014 Feb 20;426(4):921-35. doi: 10.1016/j.jmb.2013.12.002. Epub 2013 Dec 9. J Mol Biol. 2014. PMID: 24333014 Free PMC article.

5

Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments.

Kalyoncu S, Hyun J, Pai JC, Johnson JL, Entzminger K, Jain A, Heaner DP Jr, Morales IA, Truskett TM, Maynard JA, Lieberman RL. Kalyoncu S, et al. Among authors: lieberman rl. Proteins. 2014 Sep;82(9):1884-95. doi: 10.1002/prot.24542. Epub 2014 Mar 24. Proteins. 2014. PMID: 24615866 Free PMC article.

6

Molecular basis of 1-deoxygalactonojirimycin arylthiourea binding to human α-galactosidase a: pharmacological chaperoning efficacy on Fabry disease mutants.

Yu Y, Mena-Barragán T, Higaki K, Johnson JL, Drury JE, Lieberman RL, Nakasone N, Ninomiya H, Tsukimura T, Sakuraba H, Suzuki Y, Nanba E, Mellet CO, García Fernández JM, Ohno K. Yu Y, et al. Among authors: lieberman rl. ACS Chem Biol. 2014 Jul 18;9(7):1460-9. doi: 10.1021/cb500143h. Epub 2014 May 12. ACS Chem Biol. 2014. PMID: 24783948

7

Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization.

Johnson JL, Entzminger KC, Hyun J, Kalyoncu S, Heaner DP Jr, Morales IA, Sheppard A, Gumbart JC, Maynard JA, Lieberman RL. Johnson JL, et al. Among authors: lieberman rl. Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):896-906. doi: 10.1107/S1399004715001856. Epub 2015 Mar 27. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25849400 Free PMC article.

8

Catalytic Properties of Intramembrane Aspartyl Protease Substrate Hydrolysis Evaluated Using a FRET Peptide Cleavage Assay.

Naing SH, Vukoti KM, Drury JE, Johnson JL, Kalyoncu S, Hill SE, Torres MP, Lieberman RL. Naing SH, et al. Among authors: lieberman rl. ACS Chem Biol. 2015 Sep 18;10(9):2166-74. doi: 10.1021/acschembio.5b00305. Epub 2015 Jul 15. ACS Chem Biol. 2015. PMID: 26118406

9

Increased Fab thermoresistance via VH-targeted directed evolution.

Entzminger KC, Johnson JL, Hyun J, Lieberman RL, Maynard JA. Entzminger KC, et al. Among authors: lieberman rl. Protein Eng Des Sel. 2015 Oct;28(10):365-77. doi: 10.1093/protein/gzv037. Epub 2015 Aug 16. Protein Eng Des Sel. 2015. PMID: 26283664 Free PMC article.

10

Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution.

Kalyoncu S, Heaner DP Jr, Kurt Z, Bethel CM, Ukachukwu CU, Chakravarthy S, Spain JC, Lieberman RL. Kalyoncu S, et al. Among authors: lieberman rl. Nat Chem Biol. 2016 Dec;12(12):1031-1036. doi: 10.1038/nchembio.2191. Epub 2016 Oct 3. Nat Chem Biol. 2016. PMID: 27694799 Free PMC article.

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