Pintzas A - Search Results

1

IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.

Perimenis P, Galaris A, Voulgari A, Prassa M, Pintzas A. Perimenis P, et al. Among authors: pintzas a. BMC Cancer. 2016 Aug 12;16:624. doi: 10.1186/s12885-016-2606-5. BMC Cancer. 2016. PMID: 27520705 Free PMC article.

2

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, Zografos G, Oikonomou E, Pintzas A. Goulielmaki M, et al. Among authors: pintzas a. Oncotarget. 2016 Feb 23;7(8):9188-221. doi: 10.18632/oncotarget.6942. Oncotarget. 2016. PMID: 26802026 Free PMC article.

3

TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.

Oikonomou E, Kosmidou V, Katseli A, Kothonidis K, Mourtzoukou D, Kontogeorgos G, Andera L, Zografos G, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. Int J Cancer. 2009 Nov 1;125(9):2127-35. doi: 10.1002/ijc.24613. Int J Cancer. 2009. PMID: 19637313

4

The TRAIL of oncogenes to apoptosis.

Oikonomou E, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. Biofactors. 2013 Jul-Aug;39(4):343-54. doi: 10.1002/biof.1112. Epub 2013 Jun 29. Biofactors. 2013. PMID: 23813857 Review.

5

Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.

Oikonomou E, Koc M, Sourkova V, Andera L, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. PLoS One. 2011;6(6):e21632. doi: 10.1371/journal.pone.0021632. Epub 2011 Jun 27. PLoS One. 2011. PMID: 21738740 Free PMC article.

6

BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.

Makrodouli E, Oikonomou E, Koc M, Andera L, Sasazuki T, Shirasawa S, Pintzas A. Makrodouli E, et al. Among authors: pintzas a. Mol Cancer. 2011 Sep 23;10:118. doi: 10.1186/1476-4598-10-118. Mol Cancer. 2011. PMID: 21943101 Free PMC article.

7

Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.

Psahoulia FH, Drosopoulos KG, Doubravska L, Andera L, Pintzas A. Psahoulia FH, et al. Among authors: pintzas a. Mol Cancer Ther. 2007 Sep;6(9):2591-9. doi: 10.1158/1535-7163.MCT-07-0001. Mol Cancer Ther. 2007. PMID: 17876056

8

BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.

Oikonomou E, Koustas E, Goulielmaki M, Pintzas A. Oikonomou E, et al. Among authors: pintzas a. Oncotarget. 2014 Dec 15;5(23):11752-77. doi: 10.18632/oncotarget.2555. Oncotarget. 2014. PMID: 25361007 Free PMC article. Review.

9

Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.

Devetzi M, Kosmidou V, Vlassi M, Perysinakis I, Aggeli C, Choreftaki T, Zografos GN, Pintzas A. Devetzi M, et al. Among authors: pintzas a. Sci Rep. 2016 Nov 9;6:36532. doi: 10.1038/srep36532. Sci Rep. 2016. PMID: 27827395 Free PMC article.

10

BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.

Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: pintzas a. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.

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