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Page 1
An IL-17-dominant immune profile is shared across the major orphan forms of ichthyosis.
Paller AS, Renert-Yuval Y, Suprun M, Esaki H, Oliva M, Huynh TN, Ungar B, Kunjravia N, Friedland R, Peng X, Zheng X, Estrada YD, Krueger JG, Choate KA, Suárez-Fariñas M, Guttman-Yassky E. Paller AS, et al. Among authors: peng x. J Allergy Clin Immunol. 2017 Jan;139(1):152-165. doi: 10.1016/j.jaci.2016.07.019. Epub 2016 Aug 20. J Allergy Clin Immunol. 2017. PMID: 27554821 Free PMC article.
Patients with atopic dermatitis have attenuated and distinct contact hypersensitivity responses to common allergens in skin.
Correa da Rosa J, Malajian D, Shemer A, Rozenblit M, Dhingra N, Czarnowicki T, Khattri S, Ungar B, Finney R, Xu H, Zheng X, Estrada YD, Peng X, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E. Correa da Rosa J, et al. Among authors: peng x. J Allergy Clin Immunol. 2015 Mar;135(3):712-20. doi: 10.1016/j.jaci.2014.11.017. Epub 2015 Jan 10. J Allergy Clin Immunol. 2015. PMID: 25583101
RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.
Suárez-Fariñas M, Ungar B, Correa da Rosa J, Ewald DA, Rozenblit M, Gonzalez J, Xu H, Zheng X, Peng X, Estrada YD, Dillon SR, Krueger JG, Guttman-Yassky E. Suárez-Fariñas M, et al. Among authors: peng x. J Allergy Clin Immunol. 2015 May;135(5):1218-27. doi: 10.1016/j.jaci.2015.03.003. Epub 2015 Mar 31. J Allergy Clin Immunol. 2015. PMID: 25840722
Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.
Suárez-Fariñas M, Ungar B, Noda S, Shroff A, Mansouri Y, Fuentes-Duculan J, Czernik A, Zheng X, Estrada YD, Xu H, Peng X, Shemer A, Krueger JG, Lebwohl MG, Guttman-Yassky E. Suárez-Fariñas M, et al. Among authors: peng x. J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24. J Allergy Clin Immunol. 2015. PMID: 26316095
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.
Noda S, Suárez-Fariñas M, Ungar B, Kim SJ, de Guzman Strong C, Xu H, Peng X, Estrada YD, Nakajima S, Honda T, Shin JU, Lee H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E. Noda S, et al. Among authors: peng x. J Allergy Clin Immunol. 2015 Nov;136(5):1254-64. doi: 10.1016/j.jaci.2015.08.015. Epub 2015 Oct 1. J Allergy Clin Immunol. 2015. PMID: 26428954
Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin.
Esaki H, Brunner PM, Renert-Yuval Y, Czarnowicki T, Huynh T, Tran G, Lyon S, Rodriguez G, Immaneni S, Johnson DB, Bauer B, Fuentes-Duculan J, Zheng X, Peng X, Estrada YD, Xu H, de Guzman Strong C, Suárez-Fariñas M, Krueger JG, Paller AS, Guttman-Yassky E. Esaki H, et al. Among authors: peng x. J Allergy Clin Immunol. 2016 Dec;138(6):1639-1651. doi: 10.1016/j.jaci.2016.07.013. Epub 2016 Sep 23. J Allergy Clin Immunol. 2016. PMID: 27671162
Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis.
Guttman-Yassky E, Ungar B, Malik K, Dickstein D, Suprun M, Estrada YD, Xu H, Peng X, Oliva M, Todd D, Labuda T, Suarez-Farinas M, Bissonnette R. Guttman-Yassky E, et al. Among authors: peng x. J Allergy Clin Immunol. 2017 Oct;140(4):1032-1042.e13. doi: 10.1016/j.jaci.2017.01.027. Epub 2017 Feb 24. J Allergy Clin Immunol. 2017. PMID: 28238742 Free article. Clinical Trial.
Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature.
Malik K, He H, Huynh TN, Tran G, Mueller K, Doytcheva K, Renert-Yuval Y, Czarnowicki T, Magidi S, Chou M, Estrada YD, Wen HC, Peng X, Xu H, Zheng X, Krueger JG, Paller AS, Guttman-Yassky E. Malik K, et al. Among authors: peng x. J Allergy Clin Immunol. 2019 Feb;143(2):604-618. doi: 10.1016/j.jaci.2018.03.021. Epub 2018 May 24. J Allergy Clin Immunol. 2019. PMID: 29803800 Free PMC article.
Atopic dermatitis in Chinese patients shows TH2/TH17 skewing with psoriasiform features.
Chan TC, Sanyal RD, Pavel AB, Glickman J, Zheng X, Xu H, Cho YT, Tsai TF, Wen HC, Peng X, Cueto I, Krueger JG, Guttman-Yassky E. Chan TC, et al. Among authors: peng x. J Allergy Clin Immunol. 2018 Sep;142(3):1013-1017. doi: 10.1016/j.jaci.2018.06.016. Epub 2018 Jun 28. J Allergy Clin Immunol. 2018. PMID: 29964056 No abstract available.
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