Hecht SM - Search Results

1

Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting.

Chevalier A, Zhang Y, Khdour OM, Kaye JB, Hecht SM. Chevalier A, et al. Among authors: hecht sm. J Am Chem Soc. 2016 Sep 21;138(37):12009-12. doi: 10.1021/jacs.6b06229. Epub 2016 Sep 7. J Am Chem Soc. 2016. PMID: 27571326

2

The topopyrones poison human DNA topoisomerases I and II.

Khan QA, Elban MA, Hecht SM. Khan QA, et al. Among authors: hecht sm. J Am Chem Soc. 2008 Oct 1;130(39):12888-9. doi: 10.1021/ja805421b. Epub 2008 Sep 6. J Am Chem Soc. 2008. PMID: 18774813

3

Synthesis and characterization of Deltalac-acetogenins that potently inhibit mitochondrial complex I.

Chapuis JC, Khdour O, Cai X, Lu J, Hecht SM. Chapuis JC, et al. Among authors: hecht sm. Bioorg Med Chem. 2009 Mar 15;17(6):2204-9. doi: 10.1016/j.bmc.2008.10.071. Epub 2008 Nov 5. Bioorg Med Chem. 2009. PMID: 19027304

4

Carbohydrate dependent targeting of cancer cells by bleomycin-microbubble conjugates.

Chapuis JC, Schmaltz RM, Tsosie KS, Belohlavek M, Hecht SM. Chapuis JC, et al. Among authors: hecht sm. J Am Chem Soc. 2009 Feb 25;131(7):2438-9. doi: 10.1021/ja8091104. J Am Chem Soc. 2009. PMID: 19187019 Free PMC article.

5

Does oxidative stress contribute to the pathology of Friedreich's ataxia? A radical question.

Armstrong JS, Khdour O, Hecht SM. Armstrong JS, et al. Among authors: hecht sm. FASEB J. 2010 Jul;24(7):2152-63. doi: 10.1096/fj.09-143222. Epub 2010 Mar 10. FASEB J. 2010. PMID: 20219987 Review.

6

Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors.

Leiris SJ, Khdour OM, Segerman ZJ, Tsosie KS, Chapuis JC, Hecht SM. Leiris SJ, et al. Among authors: hecht sm. Bioorg Med Chem. 2010 May 15;18(10):3481-93. doi: 10.1016/j.bmc.2010.03.070. Epub 2010 Mar 31. Bioorg Med Chem. 2010. PMID: 20456960 Free PMC article.

7

Design, synthesis, and evaluation of an α-tocopherol analogue as a mitochondrial antioxidant.

Lu J, Khdour OM, Armstrong JS, Hecht SM. Lu J, et al. Among authors: hecht sm. Bioorg Med Chem. 2010 Nov 1;18(21):7628-38. doi: 10.1016/j.bmc.2010.08.030. Epub 2010 Aug 26. Bioorg Med Chem. 2010. PMID: 20884213

8

Characterization of bleomycin cleavage sites in strongly bound hairpin DNAs.

Giroux RA, Hecht SM. Giroux RA, et al. Among authors: hecht sm. J Am Chem Soc. 2010 Dec 1;132(47):16987-96. doi: 10.1021/ja107228c. Epub 2010 Nov 3. J Am Chem Soc. 2010. PMID: 21047076

9

An acetate prodrug of a pyridinol-based vitamin E analogue.

Khdour OM, Lu J, Hecht SM. Khdour OM, et al. Among authors: hecht sm. Pharm Res. 2011 Nov;28(11):2896-909. doi: 10.1007/s11095-011-0491-9. Epub 2011 Jul 6. Pharm Res. 2011. PMID: 21732153

10

Simplified bicyclic pyridinol analogues protect mitochondrial function.

Cai X, Khdour OM, Jaruvangsanti J, Hecht SM. Cai X, et al. Among authors: hecht sm. Bioorg Med Chem. 2012 Jun 1;20(11):3584-95. doi: 10.1016/j.bmc.2012.03.075. Epub 2012 Apr 13. Bioorg Med Chem. 2012. PMID: 22560834

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