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Page 1
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.
Leppkes M, Maueröder C, Hirth S, Nowecki S, Günther C, Billmeier U, Paulus S, Biermann M, Munoz LE, Hoffmann M, Wildner D, Croxford AL, Waisman A, Mowen K, Jenne DE, Krenn V, Mayerle J, Lerch MM, Schett G, Wirtz S, Neurath MF, Herrmann M, Becker C. Leppkes M, et al. Nat Commun. 2016 Mar 11;7:10973. doi: 10.1038/ncomms10973. Nat Commun. 2016. PMID: 26964500 Free PMC article.
Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs.
Maueröder C, Mahajan A, Paulus S, Gößwein S, Hahn J, Kienhöfer D, Biermann MH, Tripal P, Friedrich RP, Munoz LE, Neurath MF, Becker C, Schett GA, Herrmann M, Leppkes M. Maueröder C, et al. Among authors: leppkes m. Front Immunol. 2016 Dec 9;7:583. doi: 10.3389/fimmu.2016.00583. eCollection 2016. Front Immunol. 2016. PMID: 28018350 Free PMC article.
Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.
Kienhöfer D, Hahn J, Stoof J, Csepregi JZ, Reinwald C, Urbonaviciute V, Johnsson C, Maueröder C, Podolska MJ, Biermann MH, Leppkes M, Harrer T, Hultqvist M, Olofsson P, Munoz LE, Mocsai A, Herrmann M, Schett G, Holmdahl R, Hoffmann MH. Kienhöfer D, et al. Among authors: leppkes m. JCI Insight. 2017 May 18;2(10):e92920. doi: 10.1172/jci.insight.92920. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515366 Free PMC article.
To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.
Boeltz S, Amini P, Anders HJ, Andrade F, Bilyy R, Chatfield S, Cichon I, Clancy DM, Desai J, Dumych T, Dwivedi N, Gordon RA, Hahn J, Hidalgo A, Hoffmann MH, Kaplan MJ, Knight JS, Kolaczkowska E, Kubes P, Leppkes M, Manfredi AA, Martin SJ, Maueröder C, Maugeri N, Mitroulis I, Munoz LE, Nakazawa D, Neeli I, Nizet V, Pieterse E, Radic MZ, Reinwald C, Ritis K, Rovere-Querini P, Santocki M, Schauer C, Schett G, Shlomchik MJ, Simon HU, Skendros P, Stojkov D, Vandenabeele P, Berghe TV, van der Vlag J, Vitkov L, von Köckritz-Blickwede M, Yousefi S, Zarbock A, Herrmann M. Boeltz S, et al. Among authors: leppkes m. Cell Death Differ. 2019 Mar;26(3):395-408. doi: 10.1038/s41418-018-0261-x. Epub 2019 Jan 8. Cell Death Differ. 2019. PMID: 30622307 Free PMC article. Review.
Extracellular DNA traps in inflammation, injury and healing.
Daniel C, Leppkes M, Muñoz LE, Schley G, Schett G, Herrmann M. Daniel C, et al. Among authors: leppkes m. Nat Rev Nephrol. 2019 Sep;15(9):559-575. doi: 10.1038/s41581-019-0163-2. Epub 2019 Jun 18. Nat Rev Nephrol. 2019. PMID: 31213698 Review.
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